The David H. Koch Institute for Integrative Cancer Research at MITThe David H. Koch Institute for Integrative Cancer Research at MIT

Massachusetts Institute of Technology

National Cancer Institute Cancer Center

Science + Engineering... Conquering Cancer Together

Summer Symposium 2011

Fueling Cancer: New Advances in Metabolism and Disease

June 10, 2011

NOTE: On November 3, 2015, MIT TechTV suffered a loss of all video data, affecting the videos below. To view a subset of this content, please visit the 2011 Koch Institute Symposium playlist on YouTube. We are currently in conversation with MIT's Office of Digital Learning to determine whether the remaining videos can be recovered. Thank you for your patience.

Welcome and Opening Remarks

Tyler Jacks, Director, David H. Koch Institute for Integrative Cancer Research
Matthew Vander Heiden, David H. Koch Institute for Integrative Cancer Research

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Session 1:  Metabolic Regulation

Moderator: Jacqueline Lees

mTOR signaling and cancer metabolism

David Sabatini, Whitehead Institute
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Regulation of tumor cell metabolism by Mitochondrial Sirtuins

Marcia Haigis, Harvard Medical School
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Myc and HIF regulation of metabolism and therapeutic targets

Chi Van Dang, Johns Hopkins University School of Medicine
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Session 2: Probing Metabolism

Moderator: Paula Hammond

Imaging tumor metabolism with hyperpolarized MRI - Detecting response to treatment

Kevin Brindle, University of Cambridge

Mapping Dysregulated Metabolic Pathways in Cancer by Activity-Based Proteomics

Benjamin Cravatt, The Scripps Research Institute
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Session 3: Metabolism and Disease

Moderator: Richard Hynes

What oncogenic metabolites are teaching us about cancer

Craig Thompson, Memorial Sloan-Kettering Cancer Center
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Regulation of metabolic pathways to support cell proliferation

Matthew Vander Heiden, David H. Koch Institute for Integrative Cancer Research

HIFs, Myc, and Metabolism

M. Celeste Simon, University of Pennsylvania School of Medicine
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Role of autophagy in cancer and therapy

Eileen White, The Cancer Institute of New Jersey / UMDNG

 

Closing Remarks

Tyler Jacks, Director, David H. Koch Institute for Integrative Cancer Research