The David H. Koch Institute for Integrative Cancer Research at MITThe David H. Koch Institute for Integrative Cancer Research at MIT

Massachusetts Institute of Technology

National Cancer Institute Cancer Center

Science + Engineering... Conquering Cancer Together

Microwells

Creating novel devices for cancer detection and monitoring

Early detection and monitoring is critical to mounting effective cancer treatments. The molecular differences that make cancer cells lethal when left unchecked also provide the clues for their detection, identification and visualization.

KI Building

NCI-designated cancer center

As a National Cancer Institute-designated center for four decades, and as one of only seven NCI-designated basic research centers, MIT is at the center of the nation's efforts to conquer cancer.

Mural

Koch Institute Public Galleries

Visitors to the Koch Institute Public Galleries can explore current cancer research projects, examine striking biomedical images, hear personal reflections on cancer and cancer research and investigate the historical, geographical and scientific contexts out of which the Koch Institute emerged.

Robotic arm

Swanson Biotechnology Center

These 14 shared biotechnology laboratories provide state-of-the-art tools and specialized expertise to Koch Institute researchers, while also bringing together scientists and engineers to foster interdisciplinary collaboration.

Research scientist

Research at the Koch Institute

The Koch Institute brings scientists and engineers together to solve the problems of cancer.  We have identified five areas of research that we believe are critical for rapid progress toward controlling cancer.

Scientists

People

In creating a new era for cancer research, the Koch Institute’s greatest assets are its people. Our world renowned faculty unites leadership in multiple fields of science and engineering with a commitment to truly interdisciplinary collaboration.

Bioflash

Outreach

The Koch Institute engages public audiences of all ages and backgrounds in current cancer research through a variety of public events, youth outreach programs, and online resources about new cancer solutions.

News + Events

Phillip Sharp, Richard Hynes, Tyler Jacks, and Matt Vander Heiden

KI Directors Panel on December 14

Current and past directors Matthew Vander Heiden, Tyler Jacks, Richard Hynes, and Phil Sharp join moderator Susan Hockfield at 6:30 p.m. on Tuesday, December 14 to reflect on the progress of the last five decades and look ahead at the Koch Institute’s next ten years. more...

Blue-stained protein found on dendritic cell surfaces

immune Cell Masquerade

Spranger Lab researchers describe how a subset of immune cells infiltrate tumors and disguise themselves as cancer cells to activate killer T cells. more...

Jette Lengefeld pipettes in the lab

Stem Cells Loom Large as Aging Factor

New research from the Amon Lab suggests that stem cell size is an important factor in cellular aging. more...

aerial view of MIT campus and bridge over the Charles River

$25M gift to accelerate cancer research

The Commonwealth Foundation for Cancer Research has pledged $25 million to the Bridge Project, a collaborative research program of MIT’s Koch Institute and Dana-Farber/Harvard Cancer Centero transform drug discovery and early-stage development. more...

People

Inside the Lab: Michael Cima

Learn more about the work that Professor Cima’s lab is doing to create tiny nanosensors that are chemically sensitive to different molecules – and how they hope these sensors can be used to help determine proper dosage for chemotherapy.

Research

Our research is conducted in five areas:

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Nano-based Drugs

Nano-based Drugs

Developing nanotechnology-based cancer therapeutics... more

Detection + Monitoring

Detection + Monitoring

Creating novel devices for cancer detection and monitoring... more

Metastasis

Metastasis

Exploring the molecular and cellular basis of metastasis... more

Personalized Medicine

Personalized Medicine

Advancing personalized medicine through analysis of cancer pathways and drug resistance... more

Cancer Immunology

Cancer Immunology

Engineering the immune system to fight cancer... more

Support

With your support, we aim to improve the lives of cancer patients. Our expert cancer biologists and engineers work in tandem to tackle today's most challenging cancer problems and deliver solutions that lead to longer, healthier lives.

Your contributions can make a difference in the fight against cancer. We welcome your help to continue our progress.

Approach

Center of Cancer Nanotechnology Excellence

The MIT-Harvard Center for Cancer Nanotechnology Excellence is a collaborative effort among MIT, Harvard University, Harvard Medical School, Massachusetts General Hospital, and Brigham and Women's Hospital. more

Making Tumors Vulnerable

Watch this animation to learn how the Bhatia lab uses nanomaterials to make tumors more susceptible to treatment. more

Sensing Cancer

Watch this animation to see how a tiny, implantable sensor developed by the Cima lab could enable continuous monitoring of cancer. more

Stopping the Spread of Cancer

Watch this animation to learn about the Gertler lab's efforts to understand and fight the deadly process of metastasis. more

Engineering the Immune System

Watch this animation to learn how the Irvine lab uses nanomaterials-based "cell backpacks" to boost the immune response to cancer. more

Cutting off Cancer's Food Supply

Watch this animation to learn how the Vander Heiden lab is working to understand and target cancer metabolism. more

Bridge Project

The Bridge Project is a collaboration between the Koch Institute and the Dana-Farber/Harvard Cancer Center (DF/HCC), designed to bring bioengineering and clinical oncology together to solve today’s most challenging problems in cancer research and care.

with/in/sight Lecture Series

Join us for a series of evening programs that bring together diverse expert perspectives to discuss emerging cancer solutions.