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Photo of Tyler Jacks standing in front of a wall of colorful scientific images in the Koch Institute lobby and smiling for the camera.

Tyler Jacks Receives ACS Medal of Honor

American Cancer Society

Congratulations to Koch Institute Founding Director Tyler Jacks, who has been selected to receive the 2026 American Cancer Society Medal of Honor. The organization’s highest honor, this award is given to individuals whose work has fundamentally advanced the fight against cancer. Jacks is recognized for his extraordinary scientific contributions to the field of cancer biology as well as his leadership in shaping new, more effective models for collaborative, patient-centered research at MIT, non-profit Break Through Cancer, and the national level. 

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Immune Action at a Distance

MIT News

The Traverso Lab developed a gel-based platform for injecting immune-stimulating drugs directly into tumors. Ideally, direct injection of these drugs into a tumor will provoke a system-wide immune response, while avoiding the serious toxic side effects of systemic administration. In practice, tumors are difficult to target with precision and the drugs tend to leak away from the tumor too quickly. The team worked with colleagues at Mass General Brigham to design a thermoresponsive gel that is visible with a CT scanner, solidifies after injection, and releases drugs at a controlled rate. An Advanced Healthcare Materials study showed that in combination with checkpoint blockade therapy, the platform caused both treated tumors and untreated tumors at other locations to regress in mouse models.

Congratulations to our 2023 Karches Prize Winners

MIT Koch Institute

The annual Peter Karches Mentorship Prize recognizes the exemplary mentorship of up to four postdoctoral researchers, graduate students or technicians from across Koch Institute laboratories. This year’s recipients are Ryuhjin (Angela) Ahn, Mushriq Al-Jazrawe, Colin Fowler, and B.J. Kim. Congratulations to all!

Multi-Molecule Tracker

MIT News

Using fluorescent labels that switch on and off, the Boyden Lab has developed a method for simultaneously tracking several molecular interactions inside the cell. The technique, described in Cell, could help researchers better understand what happens inside cells, including in diseases such as cancer.

KI Faculty Members win Mark Foundation ASPIRE Award

The Mark Foundation

Cheers to the Koch Institute's four recipients of the 2023 Mark Foundation Aspire Award! Darrell Irvine and Dane Wittrup received an award for their project, “Induction of Tumor-Eradicating Systemic Immunity via Leukocyte-Targeted Cytokine Therapy.” Regina Barzilay and Tyler Jacks won an award in support their work to develop “AI-Driven Modeling of T Cell Receptors.”

Birnbaum Named Pew Innovation Fund Investigator

MIT News

Congratulations to Michael Birnbaum on being named a Pew Innovation Fund Investigator. Together with co-winner Dan Littman, he will investigate how microbes and antigens drive harmful immune responses in the gut in inflammatory bowel disease.

In Memoriam, Dr. Arthur Gelb, 1937-2023

MIT Koch Institute

With sadness, the KI marks the passing of long-time supporter Art Gelb, ScD ’61 (XVI), whose advocacy and philanthropy played key roles in the launch of the Bridge Project. The Bridge Project launched shortly after the opening of the Koch Institute and has continued to grow, enabling work by dozens of teams who are developing notable advances in cancer detection, monitoring, and treatment. We gratefully acknowledge Gelb’s vision, commitment, and generosity, and are honored to be part of his living legacy via the Bridge Project.

Introducing the 2023-2024 Convergence Scholars

MIT Koch Institute

The Marble Center for Cancer Nanomedicine and the MIT Center for Precision Cancer Medicine are pleased to announce the 2023-2024 class of Convergence Scholars. Founded in 2017, the Convergence Scholars Program (CSP) is designed to enhance the career development of aspiring independent scientists with diverse interests across academia, industry, science communication, and STEM outreach. This year's scholars are Jonuelle Acosta (Hemann Lab), Margaret Billingsley (Hammond Lab), Asheley Chapman (Irvine Lab), Allison Greaney (Langer Lab), Yizong Hu (Anderson Lab), Vardhman Kumar (Bhatia Lab), Corey Stevens (Belcher Lab), Elen Torres (Spranger Lab), and Bocheng Wu (Koehler Lab).

10 Years of the Bridge Project

MIT Koch Institute

In large part the brainchild of the late Art Gelb, ScD ’61, the Bridge Project was launched in 2012 with a simple idea uniquely suited to Greater Boston. Designed to leverage the collective expertise of MIT and Harvard, particularly its clinical cancer centers and teaching hospitals, the program’s goal is to enable collaborative research teams combining innovative science, tools and technologies with the translational expertise of clinical oncologists to solve challenging problems in cancer.  

Transformations in Cancer Care

Washington Post Live

Although cancer mortality rates have declined overall, roughly 2 million people will be diagnosed with cancer and 600,000 Americans will die from the disease this year. Robert Weinberg talks to Washington Post Live about the state of cancer research and how technological advancements are transforming cancer detection and treatment. 

Moving the Needle on Appendiceal Cancer

MIT Koch Institute

Co-hosted by MIT’s Laboratory for Financial Engineering and Koch Institute for Integrative Cancer Research, the workshop “New Approaches to Accelerating Biomedical Innovation: Case Study on Appendiceal Cancer” brought together stakeholders across academia, industry, patient advocacy groups, and regulatory spaces to lay a foundation for accelerating the development of new treatments for cancer of the appendix—a disease with few effective treatments and a low survival rate.