In celebration of their 40th anniversary, The Scientist catches up with Sangeeta Bhatia since her profiles in 2006 and 2013, giving her an opportunity to reflect on her journey in pioneering liver research, developing advanced diagnostics, and launching multiple companies. She emphasizes that she never expected her career to take this path: “We're all so focused on being strategic and planning our journey, and the truth of the matter is that the field I ended up in didn't exist on the day I graduated. The best things that happen are surprises.”