The Jaklenec and Langer groups developed a new way to preserve CAR-T cells using naturally occurring sugars, reducing the need for chemical “antifreeze” typically used to protect cells during freezing. Their findings, published in Trends in Biotechnology, could help make CAR-T cell therapy more accessible by simplifying cell storage and shipping.
This work was supported by the Koch Institute’s Convergence Scholars Program and postdoctoral fellowships supported by the Virginia and D.K. Ludwig Fund for Cancer Research.