Brush Up Your Combination Therapy

A study appearing in Nature Nanotechnology describes how bottlebrush nanoparticles are able to co-deliver multiple cancer drugs to tumors. Working with former Charles W. (1955) and Jennifer C. Johnson Clinical Investigator Peter Ghoroghchian and others, KI member Jeremiah Johnson demonstrates how his lab’s signature technology allows researchers to adjust the ratio of drugs to maximize synergistic effects. The platform could be used to identify new combination therapies or improve effectiveness of already-approved drugs.