The Ins and Outs of Metastasis

The Manalis Lab, in collaboration with the Jacks Lab, uses a novel cell-counting device to measure the frequency at which tumors shed circulating tumor cells into the bloodstream and how long these CTCs remain in circulation before being cleared by the body. The team's findings, published in Nature Communications, offer a detailed view into the dynamics of metastasis and lay the groundwork for analyzing drug response in real time. This work was supported in part by the Ludwig Center at MIT.