Examining Kendall Square's transformation from “parking lots and gravel pits” to the epicenter of a biotech boom-town, Spectrum spoke with KI member and Kronos Bio founder Angela Koehler about her own journey from academia to industry. Her laboratory’s signature small molecule microarray technology uses chemical probes to screen for compounds that can fight back against some of the most recalcitrant targets in oncology. Kronos Bio stands poised to turn these “hits” into real blockbusters—taking both cancer research and Kendall Square by storm.