“Fascinating and daunting” is how KI director Tyler Jacks describes tumors in Episode 10 of STAT’s SIGNAL podcast. Jacks joined former advisor and Nobel Prize winner Harold Varmus and others to talk with STAT’s Luke Timmerman and Meg Tirrell about cancer’s dirty, sneaky ability to evolve, evading both the immune system and treatment, in “Cancer is a low-down, gangster ninja.” Listen online; Jacks makes his first of several appearances around the five-minute mark.