News

Photo of group of people standing in front of the U.S. Capitol Building

MIT Advocacy in Action at the AACR’s 2025 Hill Day

Koch Institute

MIT Koch Institute postdoc Meaghan McGeary traveled to Washington, DC to advocate for increased federal funding for cancer research as part of the annual American Association for Cancer Research (AACR) Hill Day. Joining other early-career scientists in a mission to make more than 50 congressional visits in a single day, she shared her experiences with policymakers, emphasizing the importance of stable research funding.  

Filter by

Filter by Title/Description

Filter by Topic

Filter by Year

BIG Congratulations

American Federation for Aging Research

Cheers to Ömer Yilmaz on receiving a 2022 Glen Foundation for Medical Research BIG Award! Yilmaz will use the award to investigate the molecular mechanisms of how the stromal niche regulates intestinal stem cells in aging and how dietary interventions can reverse some of these changes.

A Mind for Metabolism

MIT News

Alejandra Rosario, a senior at the University of Puerto Rico at Cayey and MSRP-Bio student, spent last summer in the Vander Heiden Lab investigating how cells' access to nutrients in the brain contributes to the persistence of glioblastoma. Inspired by the possibility of impacting patient treatments through research on the fundamental biology of cancer, Rosario hopes to continue the work in an MD/PhD program.

Menu for Cancer Research

Chemical and Engineering News

Matt Vander Heiden spoke to Chemical & Engineering News about the complex relationship between diet and cancer. The conversation covers emerging research showing that precise nutritional approaches could restrict tumor growth or improve treatment response. While diet alone is unlikely to a cure cancer, Vander Heiden said “it can make a difference, and we need to do the studies to figure that out.”
 

Cancer Moonshot Lands in Boston

MIT Koch Institute

On the 60th anniversary of President John F. Kennedy’s landmark ‘Moonshot’ speech, President Biden came to Boston to recommit the country to the Cancer Moonshot project. At the John F. Kennedy Presidential Library and Museum, Biden spoke of his determination to ‘supercharge’ the Cancer Moonshot project and highlighted many strategies for improving cancer prevention, detection, and treatment. Many of the innovations that he spoke of are deeply rooted in our research initiatives here at the Koch Institute. Koch Institute Director Matt Vander Heiden, who attended the event alongside many of our collaborators and partners, said he was most inspired by the goal to reduce mortality by 50% over the next 25 years: “While  President Biden’s goal is ambitious, it is in reach and should be done–our cancer patients and their families need us to bring our best and boldest thinking to meet the challenge."  

Bravissimo, Bob!

ABC News

Robert Langer won a 2022 Balzan Prize in recognition of his pioneering research in biopolymers and biomaterials, paving the way “for breakthroughs in the controlled release of macromolecules with many medical applications.” The prizes will be awarded by Italian President Sergio Mattarella in November in Rome.

Trace to the Primaries

MIT News

In rare cases, a cancer cannot be traced back to its tissue of origin using available diagnostic tools, leaving patients and oncologists few options for treatment. A new deep-learning approach from the Garg Lab may help classify these cancers of unknown primary by taking a closer look at developmental gene expression patterns, which are often revived or disrupted in cancer cells. Researchers trained the model on a map of correlations built from two cell atlases, one cataloging gene expression data for different tumor types and the other tracing various developmental trajectories for embryonic cells. The model, described in Cancer Discoverycan identify cancer types with a high degree of sensitivity and accuracy.

Faculty Fanfare

MIT Koch Institute

Congratulations to Angela Koehler and Ömer Yilmaz for receiving tenure from MIT. Koehler, whose laboratory builds chemical tools and methods for studying proteins that are dysregulated in cancer, is an associate professor in the Department of Biological Engineering as well as an Associate Director of the Koch Institute. Yilmaz is an associate professor in the Department of Biology. His work focuses on the effects of various diets in tissue regeneration, aging, and cancer initiation.

In other Biology news, KI member Amy Keating has been appointed head of the department. Her laboratory analyzes protein-protein interactions important for cell signaling and human health, including those implicated in cancer.

O, the Places You’ll Go

Merck

Orna Therapeutics, co-founded by Dan Anderson to engineer circular RNA therapies, announced a collaboration with Merck. Supported by an initial $150 million, the collaboration aims to develop vaccines and therapeutics for infectious diseases and cancer.

Infection Protection Detection

MIT News

KI researchers led by hematologist/oncologist and Charles W. (1955) and Jennifer C. Johnson Clinical Investigator Hojun Li have patented a blood-based lateral flow test to measure the level of Sars-CoV-2 neutralizing antibodies. The technology, for which the team is currently seeking manufacturing partners, provides valuable insight to inform decision-making around Covid-19 precautions—particularly for vulnerable patient populations—and can be customized to detect immunity against existing and future variants. The work, which was funded in part by the Holloway Foundation, was published in Cell Reports Methods. Read more at STAT News or  USA Today or watch Li’s interview on CBS Boston.

Crypt Keepers

Cell Stem Cell

The Yilmaz Lab is shedding light on how cells within intestinal crypts support intestinal stem cell (ISC) function. In a study published in Cell Stem Cell, a team of researchers led by KI postdoc Nori Goto identified two types of cells that supply an important niche factor, which they found to be implicated in homeostasis and in regenerating ISCs after injury.

This study was supported in part by the MIT Stem Cell Initiative, the Koch Institute Frontier Research Program through the Kathy and Curt Marble Cancer Research Fund, and the Bridge Project.