The David H. Koch Institute for Integrative Cancer Research at MITThe David H. Koch Institute for Integrative Cancer Research at MIT

Massachusetts Institute of Technology

National Cancer Institute Cancer Center

Science + Engineering... Conquering Cancer Together

Past Issues

Cancer Solutions 2016/62

T-Minus 10 Recs for Cancer Moonshot Liftoff; Health Care Initiatives Look to the KI; So Many Cells, (in) So Little Time; Sweet Success for KI Startups; A New Release on Life; Pearls Before STEM; Rhythm of the Night; Mandal's Work is More Than Skin Deep; Bhatia Lab Helps CRISPR See the Light; Thanks for the Memories; More Than Meets the Eye

Cancer Solutions 2016/61

Beat the Heat, Multimedia Style; Bhatia Shoots for the Moon; TED Live and Learn; Pleading Immunotherapy; KISS and Tell; Do Viruses Make You Feel Funny?; That's So Ninja; Keeping Up with the Koehlers; Podcasts with Postdocs

Cancer Solutions 2016/60

Biomedicine for the Convergent Soul; Higher Yield on Your Next Vax Return; E. coli of Duty; Trusting Ömer Yilmaz to Change the World; Tumor Wars: Subduing the Resistance; Trial by KI-ers; From Genetics to Bionics; STEM-ulating the Nation's Youth; Patently Productive; Resident Rockstars

Cancer Solutions 2016/59

Happy Birthday to Us; And here's another '5' to celebrate; Mission: Accepted; Once in a Blue Ribbon 'Moonshot'; Big PrEvents; Open Doors, Open Minds; More to Celebrate; Taking a Stand; Bridge to the Future

Cancer Solutions 2016/58

License to Killian; A Renaissance Woman for the Nano Age; No Presents, Please. We're Focused on the Future; Growing Healthy with the Gupta Lab; Paving the Way for Metastasis; Diet and Cancer; Shooting for the Moon with Paula Hammond; Fueling Cancer Growth; Timing is of the Essence; KI Undergrad Receives Gates Scholarship

Cancer Solutions 2016/57

Totally AAASome News About Susan Hockfield; A Fitting Tribute; KI Helps Surgeons Light Up Cancer; Tag-teaming Proteins; KI Engineering Solutions: Not Just for Cancer; KI Researcher Wins TED Fellowship; A CRISPR Delivery; A Cellular Family Tree; The Fault in our Cells; Cell-abrate Style with new KI-Image Inspired Jewelry

Cancer Solutions 2016/56

Tackling a Global Challenge; Yes, it's the Right Time for a 'Moonshot'; KI Welcomes New Faculty; Fellowship of the Innovators; Fresh Material(s Science); Sustained Investment for Sustained Progress; Immaculate Suppression; Once More unto the Bridge; KI Alum to head Salk Cancer Center

Cancer Solutions 2015/55

Challenge grand expands Bridge Project; The KI's corner on innovation; No retreat, no surrender; Leading the way toward more eureka moments; Researcher's digest; What's not about Bob?; All abuzz about CRISPR; Shared goals, different approaches; Transforming tomorrow today; Grand plans for cancer research; Weinberg witty and wise at with/in/sight; SQZ named Roche's new squeeze

Cancer Solutions 2015/54

Inaugural Judith Ann Lippard Memorial Lecture; The KI plays the long game; From SOLVE to selfies; Bhatia’s ideas take flight in New York; KI researchers hog the covers; Hockfield portrait unveiled; KI undergrads on the offense; Sisters drive awareness, KI research

Cancer Solutions 2015/53

Hammond heads ChemE; Pros piece together puzzles; Bugging cancer; Cell metabolism: Cancer's Achilles heel; Designing super-long-acting pills; Love talks; KI postdoc recognized as Innovator Under 35; One in ten

Cancer Solutions 2015/52

Tyler Jacks wins MIT faculty’s top honor; Programmable probiotics; From body to bedside; Freshly squeezed vaccines; Manalis Lab microfluidics go with the flow; Fights, cancer, action; (Another) Academy (Another) Award; No pain, big gain; KI labs turned inside out

Cancer Solutions 2015/51

Main attraction; Feeling festive on April 24; Open data opens minds; A biography of cancer; Doubling down on immunotherapy; A metabolic vulnerability in glioblastoma; Nano-networked drug delivery; Hot corner

Cancer Solutions 2015/50

Robert Langer wins the Queen Elizabeth Prize for Engineering; Sangeeta Bhatia elected to the National Academy of Engineering; Artsy bacteria spread science; Converging on world challenges; Four KI trainees recognized as Forbes 30 Under 30; Special delivery; Here, there, and everywhere; Getting schooled in cancer research

Cancer Solutions 2014/49

Inspiration for the holidays; A-maze-ing TEDx talk by Tyler Jacks; Curiouser and curiouser; Two new Rhodes Scholars with KI connections; Crucial convergence

Cancer Solutions 2014/48

In fond remembrance; Jacks Lab hacks genetic modeling; Bhatia’s disruptive technology nabs international acclaim; Predicting the future with amino acids; The inside story: Implantable technology improves treatment; Swallowing your next injection; Cell-ebrating style: Super models for science

Cancer Solutions 2014/47

Bridging the gap in ovarian cancer research; Head of AACR visits the KI; Spotlight on hidden ovarian tumors; Tiny technologies put up a big fight; Unique perspectives on ovarian cancer; Sisters Against Ovarian Cancer support cutting-edge KI research; Camp Kesem MIT: Letting kids be kids; Advocating for ovarian cancer patients and research

Cancer Solutions 2014/46

KI marks Ovarian Cancer Awareness Month; Sangeeta Bhatia awarded Lemelson-MIT Prize; From bench to bedside: Targeting IDH-mutant cancers; A new way to rapidly study cancer-causing mutations; Divisive thoughts on cell division; New technique allows for better study of hepatitis B and drug treatments; Dressing drug molecules in layers; RNA combination therapy for lung cancer offers promise for personalized medicine; Stand Up to Cancer raises more than $109 million

Cancer Solutions 2014/45

Celebrating Anniversaries at the Koch Institute; KI Symposium Celebrates RNA Renaissance; Langer wins Kyoto Prize, Biotechnology Heritage Award; Cancer Immunotherapy Gets Flashy; I Love the Bright Life; Sights Set on Ovarian Cancer; YAP, YAP, YAP: Talking About Cancer Pathways; Basic Research: The Bedrock of MIT; Small Particles, Big Collaborations; Lees & Weinberg Tackle Unanswered Questions

Cancer Solutions 2014/44

Cancer researchers on the rise; Expanding the playing field for RNA interference; Building bridges for award-winning melanoma research; Muñoz makes the miles count for cancer research; Double trouble for aggressive cancers; Hopkins a powerful voice for change; MIT dreamin’; Suntharalingam receives 2014 Dalton Award

Cancer Solutions 2014/43

A multi-institutional approach to genome-guided cancer medicine; Great IDH-tions; Cancer research: we're doin’ it right; Cima’s new device shows sense and sensor-bility; SU2C names new innovation in collaboration awards in honor of Phillip A. Sharp; Jacks laboratory develops novel mouse model for aggressive thyroid cancer; Three companies: Sasisekharan startups please crowd; Triple threat: a new breed of nanoparticles; Watson and Jacks share award recognition—and more; Samson laboratory develops a test to assess DNA repair systems; MIT senior seeks to enable the disabled with technology; AACR honors KI faculty and celebrates National Cancer Research Month

Cancer Solutions 2014/42

Behind the music with Michael Hemann; Hockfield explores the power of the convergence revolution; The many elements of Stephen Lippard; Dress to impress: KI research hits the runway; Genetic road map from the Jacks laboratory reveals; potential new targets for SCLC; KI collaborators edit genes to correct genetic diseases; Biogen Idec dedicates new building to Phillip A. Sharp; AACR cancer progress report urges action; Two diseases, one drug; ACS and SU2C to jointly fund a lung cancer research dream team

Cancer Solutions 2014/41

Bhatia’s paper-based urine test for cancer, a game changer; Illuminating the science of the public galleries; Belcher's work featured in The Economist; Hynes lab identifies extracellular proteins that help tumors metastasize; Hammond joins national “We The Geeks” online STEM discussion in honor of black history month; Senior Dylan Soukup fights cancer on two fronts; Sharp calls for increased links between discovery, innovation, and entrepreneurship; Dreaming big

Cancer Solutions 2014/40

Bridge project team sets new standard for in vivo discovery of new targets for cancer immunotherapy; Sneak peek at 2014 image awards exhibition; Combining biology and engineering to improve drug discovery; Irvine’s albumin-targeted vaccines hitch a ride to the lymph nodes to boost immunity; Anderson and Langer’s nature-mimicking nanoparticles; KI faculty member Angelika Amon receives Genetics Society of America Medal; Combining forces against resistant tumors; Product-based startups: Langer’s formula; Tackling metastasis with microchips & microfluidics; MIT senior takes on cancer, hockey pucks, and more

Cancer Solutions 2014/39

Welcome 2014!; Ludwig Center receives $90M for cancer research endowment at MIT; Langer receives Breakthrough Prize; Lippard lab’s new sensor tracks zinc & cancer; MetaStat licenses KI-discovered cancer biomarkers; Langer develops nanoparticle pills; KI team addresses tumor heterogeneity; Manalis measures miniscule masses; Speeding up gene discovery

Cancer Solutions 2013/38

Teaming up to ride down cancer; KI images hit the big time at MOS; Super NOVA: KI engineers 'Make More Stuff'; Shaw goes the distance for patients; KI collaborators pen history of convergence; Yaffe finds new target for cancer combination treatment; KI's Belcher inspires, one interview at a time; Lippard's chemistry overcomes cisplatin resistance

Cancer Solutions 2013/37

Picture this; Deconinck named new KI Executive Director; Hammond knocks breast cancer down, then out; Jacks recognized by Hope Funds for cancer research; Yilmaz finds new niche at the KI; Bhatia develops urine test to detect blood clots; KI's Robert Langer and BIND Therapeutics win RUSNANOPRIZE2013; Cancer metabolism: on or off?; MIT's new innovation initiative

Cancer Solutions 2013/36

Back to school at the Koch Institute; Former MIT President Hockfield joins the KI; Koehler brings new chemistry to the Koch Institute; Ghoroghchian named newest KI clinical investigator; Hammond sets sights on ovarian cancer; Love to make drugs on demand; Irvine wraps up vaccines for improved response; All work and some play in Bhatia lab; Lees hunts cancer's genetic drivers; Collaboration develops new compounds; Tribute to a friend; Sabatini and Jacks question cancer marker; KI engineers strike gold

Cancer Solutions 2013/35

Yaffe attempts special engineering feat for KI; Much ado about nano; KI collaborators link cell growth and shape changes; Engineering-biology collaboration explains tumor drug resistance; Sisters are doin' it for ovarian cancer; Sequence matters: mTORC1 phosphorylation sites & rapamycin; Cruel Summer: Cancer hijacks heat shock factor 1; Introducing Koch-mmunity Notes

Cancer Solutions 2013/34

Summer blockbusters you haven’t heard of; Small particles hit the big screen; Cancer immunology movie marathon; A little heavy summer reading; Row your boat gently down the Charles; Pink fluffy fun for Fall; Hit the Innovation Trail - to the KI!; This ain't no armchair travel

Cancer Solutions 2013/33

Tyler Jacks among the 2013 Mass General Cancer Center's One Hundred; KI members reveal new insights into the DNA damage response; Direction, direction, direction: Sharp Lab discovers how cells read genes only in the right direction; KI welcomes new Public Outreach Coordinator; Becoming metastatic: Manalis and Jacks Labs make cell mass, stiffness, and friction count; Sabatini describes protein complex that could help predict response to cancer therapy; Kiran Mazumdar-Shaw nabs Forbes Asia cover; KI team deciphers mechanisms of nanoparticle-mediated RNA interference; Stephen Lippard wins Priestley Medal; New secrets of scaffold-assisted signaling unveiled

Cancer Solutions 2013/32

In grateful tribute; Lemelson-MIT honors KI professor Angela Belcher; Lippard receives MIT's Killian Award; KILC's Terry McGuire named Top Life Sciences Investor; David Benjamin receives competitive research grant; Chemo inside out: From predicting side effects to enhancing effectiveness; American Academy of Arts and Sciences recognizes Paula Hammond; KI researchers named fellows of the inaugural class of the AACR Academy; KI member receives one of Europe's most prestigious medical awards; Master gene regulators of normal and cancer cells discovered; A Sharp eye on Kendall Square

Cancer Solutions 2013/31

$3 Million inaugural prizes awarded to two KI members; KI Image Award winners to be revealed this month; Nanomedicine at a turning point; KI members inspire youth; Tattoo-like vaccines could replace traditional ones; HHMI profiles KI's Sangeeta Bhatia; Manipulating cells may improve monitoring

Cancer Solutions 2013/30

Robert Langer receives multiple awards; Bhatia Lab develops early detection technology; Sharp reflects on Kendall Square revitalization; Exploiting cancer cells to deliver toxic molecules; NYT highlights Langer Lab's business élan; Targeting cancer's protein folding apparatus; Former KI Executive Director Joins J&J; KI member wins 2013 Award of Excellence

Cancer Solutions 2012/29

Adhesion molecules offer potential drug targets; Ultrasound boosts transdermal drug delivery; SU2C launches pediatric dream team; Building tumor microenvironments; Advances in understanding pluripotent stem cells; High risk and high reward; New targets found for lung cancer

Cancer Solutions 2012/28

Tissue scaffolds with built-in electronic sensors; Boosting key enzyme blocks tumor formation; New nanoparticles shrink ovarian cancer tumors in mice; Engineered cells take shape; New study finds cell division linked to growth rate; "Human Body on a Chip" research

Cancer Solutions 2012/27

New Cancer Drug Candidate Shows Promise; Koch Institute Symposia 2012; Paula Hammond Changing the World; 3-D Printed Network May Help Grow Artificial Liver; Enzymes May Be Key to Fighting Colon Cancer; Nucleic Acid "Origami" Improves Delivery; Langer Honored by Society of Chemical Industry

Cancer Solutions 2012/26

New promise in treating aggressive breast cancer; Bio flash mob at the KI; Targeted nanoparticles deliver antibiotics; KI member elected to National Academy of Sciences; Two KI Members elected to AAAS; Cancer drug therapy direct to tumor; Targeted drug delivery encouraging in clinic trials

Cancer Solutions 2011/25

Unique collaboration key in attack on cancer; AAAS names Phillip Sharp President-Elect for 2013; Tiny sponge-like spheres to deliver cancer treatment; Implantable device succeeds in clinical trial; KI's Associate Director Dane Wittrup elected to NAE

Cancer Solutions 2011/24

Liver-like cells hold promise for studying patient-specific responses; Imaging technology could improve brain tumor treatment; Surprising improvement in production of induced pluripotent stem (iPS) cells; How cancer cells grow with limited supplies; Cima lab profiled by ABC News

Cancer Solutions 2011/23

Platelets as a "travel kit" for tumor cell migration?; Unique surface triples stem cell growth in culture; Koch Institute recognized for energy efficiency; RNA interference inhibits inflammation; National Medal of Science awarded to KI member

Cancer Solutions 2011/22

KI director to be named to National Cancer Advisory Board; Koch Institute professor named winner of The Economist's Annual Innovation Awards; Warren Alpert Foundation Prize awarded to KI member; Understanding how tumors maintain equilibrium; Molded microparticles for better drug delivery; KI members selected as 2011 ACS Fellows

Cancer Solutions 2011/21

Drug screening enhanced through tissue engineering; Using a patch may reduce the need for conventional needles; Aging reversed in yeast cells; Microfluidic chip used to measure single cell density; Nanoparticles zero in on tumor

Cancer Solutions 2011/20

KI member awarded 2012 Priestley Medal; Vulnerable breast cancer stem cells; Turning off cancer’s growth signals; Drug found to target common oncogene; Removing one amino acid could target melanoma; Removable 'cloak' helps target tumors

Cancer Solutions 2011/19

New insights into lung cancer metastasis; Stand Up 2 Cancer Dream Team summit; Targeted cancer drugs working better; Conquering cancer symposium; Lemelson student prize winner; Drug delivery nanoparticles improve

Cancer Solutions 2011/18

MIT150 Cancer Symposium; Targeting a universal cancer weakness; Institute celebrates formal opening; Nano-sized vaccines; Damon-Runyon Innovation Award; Two more KI members named to National Academy of Engineering

Cancer Solutions 2011/17

MIT150 Cancer Symposium; Koch Institute building dedication; The power of convergence; KI member to receive MGH prize

Cancer Solutions 2010/16

Nanoparticles' direct drug delivery; Bringing drugs to tumors; Turning off cancer genes; Know thy target; New target for cancer drugs

Cancer Solutions 2010/15

Cancer hiding spot revealed; Potential prostate cancer drug delivery; New Koch Institute building opens; KI member gets Deshpande Center grant; KI member receives National Medal of Science

Cancer Solutions 2010/14

Cocktail nanoparticles improve cancer treatment; Nae awards innovation prize to KI's Langer; New way to make cancer drugs, cheaper; Unexpected twist in cancer metabolism; Winning the "War on Cancer"

Cancer Solutions 2010/13

Protein discovered with prognostic potential in leukemias; Parallel detection of gene expression; Pharmacy on the back of a cell; Better way to grow stem cells; NCI SBIR workshop coming soon

Cancer Solutions 2010/12

Protein discovered with prognostic potential in AML and CML; KI launches new academic-industrial partnership; The 9th KI Annual Oncology Conference sells out; Shining a new light on cancer pathways; Untangling how cancers spread

Cancer Solutions 2010/11

Small RNAs continue to provide big surprises; "Directed evolution" may lead to new cancer drugs; KI expands international collaboration network into India; Oncogene's secret growth formula; Rapid analysis of DNA damage now possible; KI integrative approaches to cancer research

Cancer Solutions 2010/10

Another KI member elected to NAS; KI member receives AACR Foti Award; Recruiting from the microenvironment; Why cancer drugs lose their poser; "Weighing the facts" in cancer biology; KI integrative approaches to cancer research

Cancer Solutions 2010/9

Starving a tumor; Scientist of the Year from KI faculty; KI members among "hottest" researchers; KI member awarded prestigious medical prize; Charting new approaches to glioblastoma treatment

Cancer Solutions 2010/8

KI to help lead pancreatic cancer consortium; KI to host new NCI Center of Cancer Systems Biology; Cancer cell metabolism: A new drug target; 'Nano cocktail' targets tumors; Summer Symposium expects to bring top cancer experts to MIT

Cancer Solutions 2010/7

New nano-formulation advances RNAI therapeutics; Old discovery may bring new cancer therapies; Advances in pancreatic cancer research; KI member awarded Linus Pauling medal; KI Oncology Solutions Forum 2009

Cancer Solutions 2009/6

New ovarian cancer therapy continues to improve; Nano-formulation heads toward the clinic; Possible origins of pancreatic cancer revealed; Micro-RNA mediate metastasis suppression; Cancer research gets physical

Cancer Solutions 2009/5

Making cancer a manageable disease; Beyond the biopsy - tiny cancer monitor; Ultra tiny "bees" target tumors; Screening could lead to more potent drugs; New tools to target cancer stem cells

Cancer Solutions 2009/4

Fast tracking personalized cancer care; Suppressing ovarian tumor growth shows promise; Nova profiles KI's Sangeeta Bhatia; Forbes reports how cancer drug may also slow aging; The power of local delivery

Cancer Solutions 2009/3

9th annual Koch Institute Symposium targets metastasis; RNA snippet suppresses spread of breast cancer; KI faculty named amoung the top New England innovators; KI faculty members awarded SU2C Dream Team grant; SU2C award announcement on MSNBC

Cancer Solutions 2009/2

Implanted sensor can track tumor in real-time; Gold "nanorods" show promise in detection and treatment; Jacks elected to national academy of sciences; Tyler Jacks takes the helm as President of AACR; Economist reports on convergence

Cancer Solutions 2009/1

"Fuzzy Logic'" reveals cells' inner workings; New test that may predict aggressive cancer; Emerging role of artificial livers in developing new drugs; A major advance in reprogramming skin cells into stem cells; KI grad student wins Lemelson-MIT prize