Manalis Mirrors Multiple Myeloma Response Rates

And the KI is nine for nine! Comparing measurements of cancer cell mass accumulation rates obtained using their signature cell-weighing technology to patient outcomes, a new paper in Nature Communications shows that the Manalis Lab has taken an important step in demonstrating that they can accurately predict how tumors will respond to treatment, before treatment is given. Building on previous work conducted under the auspices of the Bridge Project, researchers at the KI and Dana-Farber Cancer Institute tested a variety of drugs and combination therapies on tumor cells from nine multiple myeloma patients. In all of the pilot study's cases, measurements of cells' sensitivity and resistance in the lab matched patient response to actual treatment in the clinic. The team is now working to validate their approach in a larger clinical study and hopes to expand their investigations to include other cancer types as well.