Scientific Director, High Throughput Sciences
Contact Information
Mushriq Al-Jazrawe serves as the scientific director of the High Throughput Sciences facility in the Swanson Biotechnology Center at MIT’s Koch Institute. Al-Jazrawe and his team offer the Koch Institute community and external collaborators a comprehensive platform for data-driven discovery, providing expertise and tools for assay development, lab automation, and data analysis. The overarching goal is developing and utilizing systematic approaches to accelerate biomedical insights and expand their impact on human health.
Al-Jazrawe received his BSc in genetics, and PhD in pathobiology from the University of Toronto, conducting his graduate research at the Hospital for Sick Children in the Developmental and Stem Cell Biology program under the supervision of Dr. Benjamin Alman. He then joined the Broad Institute and the Koch Institute as a postdoctoral associate under the supervision of Dr. Jesse Boehm, where he acquired skills for high-content screening and machine learning. Al-Jazrawe is a lead contributor of the Human Cancer Model Initiative, a global effort to generate and molecularly characterize over 600 novel organoid and cell line models, highlighting his commitment to team-based science. Recognizing that modeling disease through long-term cultures remains a major bottleneck in cancer discovery, Al-Jazrawe develops experimental and computational workflows to enable rapid genetic and pharmacological perturbation of living tissues without a model generation step. Success in this area expands the range of patient samples that can be studied, enhancing preclinical discovery efforts. He also leads a multi-institute study integrating single-cell transcriptomic and genomic analyses to understand how these molecular features relate to clinical response in rare mesenchymal tumors.
In 2023, Al-Jazrawe was honored with the Peter Karches Mentorship Award, highlighting his passion for teaching and mentoring the next generation of scientists. He also serves on the scientific advisory board of the Desmoid Tumor Research Foundation.