Microscopy

fluorescent microscopy image of nanoparticles in lung tissue

The Microscopy Core Facility provides experimental consultation, fee-for-service imaging assistance, and training in and access to several imaging platforms, image acquisition equipment, and data analysis software packages.

Services include:

  • light and epifluorescence microscopy
  • fluorescent slide scanning
  • scanning confocal microscopy
  • multiphoton scanning confocal microscopy and intravital imaging
  • deconvolution-based microscopy for sensitive, high-resolution fluorescence imaging
  • 3D structured illumination microscopy
  • total internal reflection fluorescence (TIRF) microscopy
  • advanced fluorescence microscopy (FRAP- fluorescence recovery after bleaching, FRET- fluorescence resonance energy transfer, photo-recovery)
  • laser capture microdissection

Access is typically reserved for KI members. In some circumstances, access may be available to non-member MIT or external users (details available on request from the Scientific Director, Jeffrey Kuhn).

The Microscopy Core is supported in part by funding provided to the Koch Institute from a National Cancer Institute Cancer Center Support Grant.

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