Microwells

Creating novel devices for cancer detection and monitoring

Early detection and monitoring is critical to mounting effective cancer treatments. The molecular differences that make cancer cells lethal when left unchecked also provide the clues for their detection, identification and visualization.

NCI-designated cancer center

As a National Cancer Institute-designated center for almost four decades, and as one of only seven NCI-designated basic research centers, MIT is at the center of the nation's efforts to conquer cancer.

Koch Institute Public Galleries

Visitors to the Koch Institute Public Galleries can explore current cancer research projects, examine striking biomedical images, hear personal reflections on cancer and cancer research and investigate the historical, geographical and scientific contexts out of which the Koch Institute emerged.

Robotic Arm

Swanson Biotechnology Center

These 14 shared biotechnology laboratories provide state-of-the-art tools and specialized expertise to Koch Institute researchers, while also bringing together scientists and engineers to foster interdisciplinary collaboration.

Research at the Koch Institute

The Koch Institute brings scientists and engineers together to solve the problems of cancer.  We have identified five areas of research that we believe are critical for rapid progress toward controlling cancer.

People

In creating a new era for cancer research, the Koch Institute’s greatest assets are its people. Our world renowned faculty unites leadership in multiple fields of science and engineering with a commitment to truly interdisciplinary collaboration.

Outreach

The Koch Institute engages public audiences of all ages and backgrounds in current cancer research through a variety of public events, youth outreach programs, and online resources about new cancer solutions.

People

Inside the Lab: Michael Cima

Learn more about the work that Professor Cima’s lab is doing to create tiny nanosensors that are chemically sensitive to different molecules – and how they hope these sensors can be used to help determine proper dosage for chemotherapy.

Research

5 4 3 2 1

Our research is conducted in five areas:

Cancer Immunology

Cancer Immunology

Engineering the immune system to fight cancer... more

Personalized Medicine

Personalized Medicine

Advancing personalized medicine through analysis of cancer pathways and drug resistance... more

Metastasis

Metastasis

Exploring the molecular and cellular basis of metastasis... more

Detection + Monitoring

Detection + Monitoring

Creating novel devices for cancer detection and monitoring... more

Nano-based Drugs

Nano-based Drugs

Developing nanotechnology-based cancer therapeutics... more

Support

With your support, we aim to improve the lives of cancer patients. Our expert cancer biologists and engineers work in tandem to tackle today's most challenging cancer problems and deliver solutions that lead to longer, healthier lives.

Your contributions can make a difference in the fight against cancer. We welcome your help to continue our progress.

News + Events

Tyler Jacks

Life Lessons from 34 Years of Fighting Cancer

At TEDxCambridge in September, Koch Institute Director Tyler Jacks shared insights from his 34 years in the "maze" of cancer research. more...

Jacks Lab

Genome-editing technique speeds analysis of genes mutated in tumors

Using CRISPR, KI researchers from Tyler Jacks’ lab have developed a new approach to rapidly model the effects of tumor cells’ genetic mutations in mice. The researchers envision using the technique to study personalized cancer treatments by modeling mice based on the genetic profile of an individual patient’s tumor. more...

Sangeeta Bhatia

Koch Institute Member Awarded $500,000 Lemelson-MIT Prize

Dr. Sangeeta Bhatia, biomedical engineer and faculty member at the Koch Institute for Integrative Cancer Research at MIT, is the recipient of the 2014 $500,000 Lemelson-MIT Prize. Bhatia is recognized for designing and commercializing miniaturized technologies with applications to improve human health.  more...

Ovarian Cancer Awareness

Special Symposium: Bridging the Gap in Ovarian Cancer

Join us on September 16 for Bridging the Gap in Ovarian Cancer, a special symposium for ovarian cancer patients, survivors, family members, advocates, researchers, and other interested members of the public. Register here more...

Approach

Center of Cancer Nanotechnology Excellence

The MIT-Harvard Center for Cancer Nanotechnology Excellence is a collaborative effort among MIT, Harvard University, Harvard Medical School, Massachusetts General Hospital, and Brigham and Women's Hospital. more

Making Tumors Vulnerable

Watch this animation to learn how the Bhatia lab uses nanomaterials to make tumors more susceptible to treatment. more

Sensing Cancer

Watch this animation to see how a tiny, implantable sensor developed by the Cima lab could enable continuous monitoring of cancer. more

Stopping the Spread of Cancer

Watch this animation to learn about the Gertler lab's efforts to understand and fight the deadly process of metastasis. more

Engineering the Immune System

Watch this animation to learn how the Irvine lab uses nanomaterials-based "cell backpacks" to boost the immune response to cancer. more

Cutting off Cancer's Food Supply

Watch this animation to learn how the Vander Heiden lab is working to understand and target cancer metabolism. more

Koch Institute Faculty Openings

The Koch Institute invites applications for two open faculty appointments—one in the School of Engineering, and one in the School of Science. Learn more

Bridge Project

The Bridge Project is a collaboration between the Koch Institute and the Dana-Farber/Harvard Cancer Center (DF/HCC), designed to bring bioengineering and clinical oncology together to solve today’s most challenging problems in cancer research and care.

with/in/sight Lecture Series

Join us for a series of evening programs that bring together diverse expert perspectives to discuss emerging cancer solutions.