Instrumentation

Two Evo 150 Liquid Handling Decks In Baker Hood (HEPA) Enclosures

  • Small molecule library arraying and cherry picking
  • Automated cell plating, administration and removal of compounds via integrated automated CO2 incubator

Integrated Robotic Automated Assay Platform

  • BioTek 406 plate washer (cell plating and washing, ELISA-type assays)
  • Automated microplate centrifuge

Tecan M1000 Plate Reader

  • Flexible wavelength selection from UV to NIR
  • Luminescence, fluorescence intensity (top and bottom reading), TRF, TR-FRET, fluorescence polarization
  • Flexible wavelength selection from UV to NIR
  • AlphaScreen and AlphaLISA technology
  • NanoQuant Plate compatibility for nucleic acid quantification

Arrayscan Screening Microscope With Confocal Capability

  • LED Light Engine designed for high performance excite blue (e.g. Hoechst), green (e.g. FITC, GFP), orange red (e.g. TRITC), deep red (e.g.. Texas Red), and long red (e.g. Cy5) fluorochromes
  • Nipkov spinning disk technology
  • User-definable z-range with 0.1μm resolution step size for confocal slices

Bl2+ Lentiviral shRNA Screening Platform

  • Integrated robotic platform for packaging, manipulation and screening of lentiviral shRNA (RNAi) vectors