Facility Sponsors

National Cancer Institute

Biopolymers & Proteomics

Biopolymers

The Biopolymers & Proteomics Core Facility provides MIT researchers with integrated synthetic and analytical capabilities for biological materials, including proteins and peptides, as well as nanoparticles. The Core encompasses a wide range of sophisticated technical expertise and state-of-the-art instrumentation. Access is available to all members of the MIT community, to the extent permitted by available capacity. Priority access is given to KI members, NCI-funded research projects and other contributing user groups in recognition of funding support. In special circumstances, access may be available to non-MIT users (details available on request from the Core Leader Richard Cook).

Services include:

  • mass spectrometry-based proteomics approaches for identification, characterization, or quantitation of proteins from simple to complex mixtures
  • MALDI-TOF mass spectrometry
  • peptide synthesis and purification, including peptide arrays
  • high-pressure liquid chromatographic analysis and purification

Questions pertaining to our services?

For questions regarding peptide synthesis, SPOT synthesis, MALDI-TOF mass spectrometry, and HPLC separations, please email Richard Cook.

For mass spectrometry questions regarding protein identification and mass determination including small molecule MS, please email Rick Schiavoni.

For proteomics questions regarding post translational modifications or relative quantitation (iTRAQ, SILAC), please email Amanda Del Rosario.

The Biopolymers & Proteomics Core is supported in part by funding provided to the Koch Institute from a National Cancer Institute Cancer Center Support Grant.