K. Dane Wittrup

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Cancer Treatment Challenges Symposium/Roundtable

At this May 6, 2013 event, cancer biologists, engineers, and clinicians gathered at the Koch Institute at MIT for an open discussion of the greatest challenges and most promising solutions in cancer care. Speakers included:

Phillip A. Sharp, Institute Professor, Koch Institute at MIT
Sangeeta N. Bhatia, John J. and Dorothy Wilson Professor of Health Sciences and Technology & Electrical Engineering and Computer Science, Koch Institute at MIT
K. Dane Wittrup, Carbon P. Dubbs Professor of Chemical Engineering and Bioengineering, Koch Institute at MIT
Michael B. Yaffe, David H. Koch Professor of Biology and Biological Engineering, Koch Institute at MIT
Catherine J. Wu, Associate Physician, Medical Oncology, Dana-Farber Cancer Institute
Jay S. Loeffler, Chief, Radiation Oncology, Massachusetts General Hospital
Matthew R. Smith, Director, Genitourinary Malignancies Program, Massachusetts General Hospital Cancer Center
Steven P. Balk, Staff Physician, Hematology/Oncology, Beth Israel Deaconess Medical Center Hear highlights from the discussion in the video below. The event also featured presentations by researchers working on existing Bridge Project teams: Christopher Love, Koch Institute at MIT, Hidde Ploegh, Whitehead Institute and Koch Institute at MIT, and Kai W. Wucherpfennig, Dana Farber Cancer Institute
Novel Immunotherapies Against Pancreatic Cancer Elazer Edelman, Institute of Medical Engineering and Sciences at MIT and Koch Institute at MIT and Jeffrey W. Clark, Massachusetts General Hospital
A Pancreatobiliary Chemotherapy Eluting Stent for Pancreatic Ductal Adenocarcinomas Rakesh K. Jain, Massachusetts General Hospital and Robert Langer, Koch Institute at MIT
Angiotensin Receptor Blockers (ARBs) as a Novel Approach to Improve Drug Delivery in the Treatment of Pancreatic Cancer Keith L. Ligon, Dana-Farber Cancer Institute and J. Christopher Love, Koch Institute at MIT
Single-Cell Functional, Genomic and Transcriptomic Analysis in Glioblastoma watch...

NAE Honors KI's Associate Director

K. Dane Wittrup was one of five MIT engineers elected to the National Academy of Engineering. The election is one of highest professional honors awarded to an engineer. more...

Antibody binds to its target molecule. Image: Kelly Orcutt

KI researchers "fast track" directed evolution

In nature, evolution takes place over eons. But evolution can also happen on a small and fast scale in the laboratory. The approach is called "directed evolution," and scientists are using it to generate proteins that do not occur in nature – for example, cancer drugs, new microbial enzymes for converting agricultural waste to fuel, or imaging agents for magnetic resonance imaging (MRI). more...

Day 2 Opening Remarks

K. Dane Wittrup, Associate Director, Koch institute, and Carbon P. Dubbs Professor of Chemical Engineering and Bioengineering watch...

Therapeutic Antibodies

Researchers have found that antibodies do not need a particular sugar attachment long believed to be essential to their function, a discovery that could make producing therapeutic antibodies much easier and cheaper in the future. more...

Prostate cancers can escape immunity

KI researchers describe potent immuno-suppressive activity of prostate cancer microenvironment. more...