Michael J. Cima

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The inside story: Implantable technology improves treatment

Working on implantable devices for drug delivery, KI member Michael Cima, David H. Koch Professor of Engineering, hopes to make cancer treatments safer, more effective, and more convenient. As these implantable devices advance toward the clinic, so does the promise for improving patient outcomes and experiences. more...

Symposium: Osmotic Micro-Pump as Delivery System for Intraperitoneal Chemotherapy in the Treatment of Advanced Ovarian Cancer

May 22, 2014 Bridge to Success Osmotic Micro-Pump as Delivery System for Intraperitoneal Chemotherapy in the Treatment of Advanced Ovarian Cancer, a collaboration between Michael Cima of the Koch Institute, Michael Birrer of Massachusetts General Hospital, and Marcela Del Carmen of Massachusetts General Hospital watch...

Cima Develops a Sensor for Measuring Tumors’ Oxygen Levels

A new sensor for measuring oxygen levels around tumors has been developed by researchers from the laboratory of KI faculty member and David H. Koch Professor in Engineering Michael Cima. The sensor, described in the Proceedings of the National Academy of Sciences, is an injectable device made of silicone, which is picked up in MRI scans. The sensor is the first MRI contrast agent that can be left in the body for long periods of time, allowing for the collection of oxygen tension over several weeks. Given that cancer cells thrive without oxygen and tumors in low-oxygen environments are generally more aggressive and resistant to treatment, long-term monitoring of oxygen tension will provide new insights into tumor growth and could aid therapeutic choices and tracking of treatment response. more...

Technology Workshop: Michael Cima

September 20, 2012 Early Detection/Diagnostics
Michael Cima, Koch Institute watch...

KI Researchers' Implantable Device Succeeds in Clinical Trial

A drug delivery device implanted in patients proved first successful results of released drug delivery that could usher in new era of telemedicine. Along with scientists from MICROCHIPS, two David Koch professors report their findings in February 16th issue of Science Translational Medicine. more...

Cima Lab's Biosensor Profiled by ABC News

Bill Weir of ABC's Nightline visited the Cima lab to learn all about their implantable sensor, which could allow doctors to continuously and non-invasively monitor tumor environments.  The segment appeared on the ABC News program, "This Could Be Big." more...

Sensing Cancer

A tiny, implantable sensor developed by the Cima lab could enable continuous monitoring of cancer. watch...

Using A Patch May Reduce The Need For Conventional Needles

The Boston Globe reports that a drug-filled patch created by KI researchers may one day replace some of the need for conventional needles to administer injected drugs. The patch that attaches to the skin would provide small doses of medication over time in place of frequent hospital visits or bolus injections.  It could be used on chronic diseases such as cancer, multiple sclerosis, and hepatitis C.  Clinical trials could begin late next year. more...

Inside the Lab: Michael Cima

Michael Cima

Learn more about the work that Professor Cima’s lab is doing to create tiny nanosensors that are chemically sensitive to different molecules – and how they hope these sensors can be used to help determine proper dosage for chemotherapy. watch...

Linda Griffith

Two KI engineers named to the National Academy of Engineering

Michael Cima and Linda Griffith are among the 68 new members and nine foreign associates elected to the National Academy of Engineering (NAE) on Feb. 8. Election to the National Academy of Engineering is among the highest professional distinctions accorded to an engineer. Academy membership honors those who have made outstanding contributions to "engineering research, practice or education, including, where appropriate, significant contributions to the engineering literature." more...

"The Cima Seven" selected and honored

Great inventors share a common set of traits, the most important of them: curiosity, empathy and leadership. more...

Implantable monitoring device can detect tumor growth

Biopsies offer a snapshot of a tumor at a single moment in time. Monitoring a tumor for weeks or months after the biopsy, tracking its growth and how it responds to treatment, would be much more valuable, says KI scientist Michael Cima, who has developed the first implantable device that can do just that. more...

KI faculty share latest technologies at recent World Economic Forum IdeasLab Annual Meeting

Sangeeta Bhatia and Michael Cima shared their latest research at an international meeting in Davos-Klosters, Switzerland. more...