The David H. Koch Institute for Integrative Cancer Research at MIT
Science + Engineering... Conquering Cancer Together
Turning on a particular gene (a transcription factor, NTD80) in aged yeast cells, researchers in the Amon lab have doubled the cells’ usual lifespan. It could offer a new approach to rejuvenating human cells or creating pluripotent stem cells.“There’s a true rejuvenation going on, it took an old cell and made it young again,” says KI Professor Angelika Amon. more...
A KI team has identified potential drugs that amplify the cellular stress caused by too many chromosomes, known as aneuploidy. When designing new cancer drugs, biologists often target specific gene mutations found only in cancer cells, or in a subset of cancer cells. The team of biologists led by Angelica Amon from the Koch Institute is now taking a slightly different approach, targeting a trait shared by nearly all cancer cells. more...
Learn more about the Amon lab and how understanding cell division and cell stress may lead to the development of new drugs or compounds that selectively kill cancer cells. watch...
Angelika Amon is among 72 newly elected to the National Academy of Sciences, in recognition of distinguished and continuing achievements in original research. more...
Mammalian cells with extra chromosomes share some common traits that could be exploited to develop cancer treatments, according to MIT biologists. more...
MIT Professor Angelika Amon and Todd R. Golub of the Broad Institute of MIT and Harvard will share the 2007 Paul Marks Prize for Cancer Research, an award of $150,000, with Gregory J. Hannon from Cold Spring Harbor Laboratory. more...
