The Nanowell Cytometry platform is a shared resource housed in the Flow Cytometry Core that provides Koch Institute & MIT researchers access to “Microengraving” technologies, developed in the Love Laboratory at the Koch Institute.
The platform enables measurement of multiple traits from individual cells derived from a wide array of tissues or cell types, such as immune cells either in their native condition or upon stimulation. The modularity of the platform allows simultaneous assessment from small or large numbers of cells. Additionally, it is possible to obtain genetic information from the individual cells of interest.
To date, the platform has been employed in projects related to antibody discovery, tumor profiling from various cancer tissues, and immune cell functions in various allergic, infectious or auto-immune diseases.
Access to the platform is available to all members of the MIT community, to the extent permitted by available capacity. Priority access is given to KI members, NCI-funded research projects and other contributing user groups in recognition of funding support. Depending on available capacity, access may be available to non-MIT users (details available on request from platform Lead Specialist Shanu Mehta).
The Nanowell Cytometry Platform is supported in part by funding provided to the Koch Institute from a National Cancer Institute Cancer Center Support Grant.