The David H. Koch Institute for Integrative Cancer Research at MITThe David H. Koch Institute for Integrative Cancer Research at MIT

Massachusetts Institute of Technology

National Cancer Institute Cancer Center

Science + Engineering... Conquering Cancer Together

Services

Assay development and screening

  • Small molecule or lentiviral screening, including combination experiments
  • Cell-based assays (e.g. cytotoxicity, qPCR prep, etc)
  • Biochemical assays
  • Alphascreen/AlphaLISA
  • ELISA
  • High content/high throughput imaging in plate and slide format
  • General liquid handling (plating, compound delivery, serial dilutions, plate washing, etc.)
  • 96 or 384 well formats available for most screens
  • Both high throughput primary screens as well as lower throughput assays for follow-up studies
  • High throughput Western Blot detection

Additional Services

  • Mycoplasma testing
  • Cell line expansion, distribution and repository (MIT community only)
  • High throughput Chromatin Immunoprecipitation (ChIP) prep (from tissue or cells)
  • Discounted consumables (plates, media, common reagents, tips)
  • BL2+ resources, including shared workspace, training, equipment and consumables

Technical Expertise

  • Selection of assay and screening formats, assay development and optimization
  • Consulting services for researchers with specific automation or liquid handling needs
  • Tissue culture consultation
  • Engineering consultation