The David H. Koch Institute for Integrative Cancer Research at MITThe David H. Koch Institute for Integrative Cancer Research at MIT

Massachusetts Institute of Technology

National Cancer Institute Cancer Center

Science + Engineering... Conquering Cancer Together

Pricing (Mass Spectrometry)

Service Description KI MIT (non-KI)
Mass Spectrometry - MALDI-TOF Analysis $30 $60
Desalting, per sample $30 $60
Proteomics sample preparation Simple digest (gelbands; pure proteins) $70 $140
Simple digest, additional sample $21 $42
Medium complex digest (gellanes; IPs)* $100 $200
Medium digest, additional sample $30 $60
Complex digest (includes cleanup) (lysates)** $150 $300
Complex digest, additional sample $45 $90
Phosphorylation (cleanup and enrichment) $100 $200
Additional phosphorylation sample $50 $100
Tyrosine phosphorylation $150 $300
Additional phosphorylation sample $75 $150
Other PTM enrichment $300 $600
Additional PTM enrichment sample $150 $300
TMT6 (100ug) $500 $1,000
TMT10 (100ug) $917 $1,834
TMT16 (100ug) $1,334 $2,668
TMT6 (400ug) $875 $1,750
TMT10 (400ug) $1,605 $3,210
TMT16 (400ug) $2,334 $4,668
Additional cleanup (C18 cleanup) / per sample $15 $30
Protein concentration measurements $20 $40
Additional protein concentration $10 $20
Mass Spectrometry

 

MS run: simple sample (single proteins; single gel bands) $50 $100
MS run: medium complex sample (gel lanes; IPs) $75 $150
MS run: complex sample (lysate) $100 $200
PRM analysis (for up to 20 peptides) $50 $100
Data analysis

 

Data analysis (ID search) $100 $200
Data analysis (quantitation analysis; TMT; PRM; LFQ; SILAC) $100 $200
Data analysis (PTM analysis; for single protein manual verification) $100 $200
Data analysis for small molecules, pK $100 $200
MW protein analysis (LC/MS: QE analysis)   $80 $160
HPLC

 

HPLC fractionation (setup) $200 $400
HPLC (scientist usage)/hour $40 $80
HPLC (scientist usage)/day $100 $200
HPLC training $75 $150
Small molecule analysis

 

Initial setup for Quantitation (PRM) on QE (high flow) small molecules $200 $400
Calibration curve $100 $200
MRM runs for PK work (per sample) ; after initial setup and calibration curve $20 $40
Combined prices (sample preparation/LC-MS/data analysis)

 

Simple digest (sample preparation/LC-MS/data analysis) $220 $440
Additional simple digest (sample preparation/LC-MS/data analysis) $71 $142
Medium complex digest (sample preparation/LC-MS/data analysis) $275 $550
Additional medium complex digest (sample preparation/LC-MS/data analysis $105 $210
Complex digest (sample preparation/LC-MS/data analysis) $350 $700
Additional complex digest (sample preparation/LC-MS/data analysis) $145 $290
Simple digest phosphorylation (sample preparation/LC-MS/data analysis) $420 $840
Additional simple digest phosphorylation (sample preparation/LC-MS/data analysis) $121 $242
Medium complex digest phosphorylation (sample preparation/LC-MS/data analysis $475 $950
Additional medium complex digest phosporylation (sample preparation/LC-MS/data analysis) $155 $310
Complex digest phosphorylation (sample preparation/LC-MS/data analysis) $550 $1,100
Additonal complex digest phosphorylation (sample preparation/LC-MS/data analysis) $195 $390
Complex digest tyrosine phosphorylation (sample preparation/LC-MS/data analysis) $600 $1,200
Additional complex digest tyrosine phosphorylation (sample preparation/LC-MS/data analysis) $220 $440
Complex digest PTM (sample preparation/LC-MS/data analysis) $750 $1,500
Additonal complex digest PTM (sample preparation/LC-MS/data analysis) $295 $590
TMT experiments calculated with 100ug sample sizes

 

TMT6 (IP) $1,025 $2,050
TMT10 (IP) $1,562 $3,124
TMT6 (lysate) $1,175 $2,350
TMT10 (lysate) $1,772 $3,544
TMT16 (lysate) $2,459 $4,918
TMT6 (phospho experiment) $1,625 $3,250
TMT10 (phospho experiment) $2,422 $4,844
TMT16 (phospho experiment) $3,409 $6,818
TMT6 (tyrosine experiment) $1,800 $3,600
TMT10 (tyrosine experiment) $2,697 $5,394
TMT16 (tyrosine experiment) $3,834 $7,668
TMT6 (other PTM experiment) $2,325 $4,650
TMT10 (other PTM experiment) $3,522 $7,044
TMT16 (other PTM experiment) $5,109 $10,218

*normally includes a C18 cleanup (back to top)
**normally includes using a STrap, precipitation or other C18 based method, more enzyme, could include protein conc measurement (back to top)

The above fee schedule is effective as of July 1, 2020.

Note: rates are set periodically, based on operating costs and in accordance with MIT and NCI policies. They are reviewed and approved annually by the MIT Office of Cost Analysis. Services are billed at the rate listed on the date of service delivery.