Pricing (Mass Spectrometry)
| Service | Description | KI | MIT (non-KI) |
|---|---|---|---|
| Mass Spectrometry - MALDI-TOF | Analysis | $30 | $60 |
| Desalting, per sample | $30 | $60 | |
| Proteomics sample preparation | Simple digest (gelbands; pure proteins) | $70 | $140 |
| Simple digest, additional sample | $21 | $42 | |
| Medium complex digest (gellanes; IPs)* | $100 | $200 | |
| Medium digest, additional sample | $30 | $60 | |
| Complex digest (includes cleanup) (lysates)** | $150 | $300 | |
| Complex digest, additional sample | $45 | $90 | |
| Phosphorylation (cleanup and enrichment) | $100 | $200 | |
| Additional phosphorylation sample | $50 | $100 | |
| Tyrosine phosphorylation | $150 | $300 | |
| Additional phosphorylation sample | $75 | $150 | |
| Other PTM enrichment | $300 | $600 | |
| Additional PTM enrichment sample | $150 | $300 | |
| TMT6 (100ug) | $500 | $1,000 | |
| TMT10 (100ug) | $917 | $1,834 | |
| TMT16 (100ug) | $1,334 | $2,668 | |
| TMT6 (400ug) | $875 | $1,750 | |
| TMT10 (400ug) | $1,605 | $3,210 | |
| TMT16 (400ug) | $2,334 | $4,668 | |
| Additional cleanup (C18 cleanup) / per sample | $15 | $30 | |
| Protein concentration measurements | $20 | $40 | |
| Additional protein concentration | $10 | $20 | |
| Mass Spectrometry
|
MS run: simple sample (single proteins; single gel bands) | $50 | $100 |
| MS run: medium complex sample (gel lanes; IPs) | $75 | $150 | |
| MS run: complex sample (lysate) | $100 | $200 | |
| PRM analysis (for up to 20 peptides) | $50 | $100 | |
| Data analysis
|
Data analysis (ID search) | $100 | $200 |
| Data analysis (quantitation analysis; TMT; PRM; LFQ; SILAC) | $100 | $200 | |
| Data analysis (PTM analysis; for single protein manual verification) | $100 | $200 | |
| Data analysis for small molecules, pK | $100 | $200 | |
| MW protein analysis (LC/MS: QE analysis) | $80 | $160 | |
| HPLC
|
HPLC fractionation (setup) | $200 | $400 |
| HPLC (scientist usage)/hour | $40 | $80 | |
| HPLC (scientist usage)/day | $100 | $200 | |
| HPLC training | $75 | $150 | |
| Small molecule analysis
|
Initial setup for Quantitation (PRM) on QE (high flow) small molecules | $200 | $400 |
| Calibration curve | $100 | $200 | |
| MRM runs for PK work (per sample) ; after initial setup and calibration curve | $20 | $40 | |
| Combined prices (sample preparation/LC-MS/data analysis)
|
Simple digest (sample preparation/LC-MS/data analysis) | $220 | $440 |
| Additional simple digest (sample preparation/LC-MS/data analysis) | $71 | $142 | |
| Medium complex digest (sample preparation/LC-MS/data analysis) | $275 | $550 | |
| Additional medium complex digest (sample preparation/LC-MS/data analysis | $105 | $210 | |
| Complex digest (sample preparation/LC-MS/data analysis) | $350 | $700 | |
| Additional complex digest (sample preparation/LC-MS/data analysis) | $145 | $290 | |
| Simple digest phosphorylation (sample preparation/LC-MS/data analysis) | $420 | $840 | |
| Additional simple digest phosphorylation (sample preparation/LC-MS/data analysis) | $121 | $242 | |
| Medium complex digest phosphorylation (sample preparation/LC-MS/data analysis | $475 | $950 | |
| Additional medium complex digest phosporylation (sample preparation/LC-MS/data analysis) | $155 | $310 | |
| Complex digest phosphorylation (sample preparation/LC-MS/data analysis) | $550 | $1,100 | |
| Additonal complex digest phosphorylation (sample preparation/LC-MS/data analysis) | $195 | $390 | |
| Complex digest tyrosine phosphorylation (sample preparation/LC-MS/data analysis) | $600 | $1,200 | |
| Additional complex digest tyrosine phosphorylation (sample preparation/LC-MS/data analysis) | $220 | $440 | |
| Complex digest PTM (sample preparation/LC-MS/data analysis) | $750 | $1,500 | |
| Additonal complex digest PTM (sample preparation/LC-MS/data analysis) | $295 | $590 | |
| TMT experiments calculated with 100ug sample sizes
|
TMT6 (IP) | $1,025 | $2,050 |
| TMT10 (IP) | $1,562 | $3,124 | |
| TMT6 (lysate) | $1,175 | $2,350 | |
| TMT10 (lysate) | $1,772 | $3,544 | |
| TMT16 (lysate) | $2,459 | $4,918 | |
| TMT6 (phospho experiment) | $1,625 | $3,250 | |
| TMT10 (phospho experiment) | $2,422 | $4,844 | |
| TMT16 (phospho experiment) | $3,409 | $6,818 | |
| TMT6 (tyrosine experiment) | $1,800 | $3,600 | |
| TMT10 (tyrosine experiment) | $2,697 | $5,394 | |
| TMT16 (tyrosine experiment) | $3,834 | $7,668 | |
| TMT6 (other PTM experiment) | $2,325 | $4,650 | |
| TMT10 (other PTM experiment) | $3,522 | $7,044 | |
| TMT16 (other PTM experiment) | $5,109 | $10,218 |
*normally includes a C18 cleanup (back to top)
**normally includes using a STrap, precipitation or other C18 based method, more enzyme, could include protein conc measurement (back to top)
The above fee schedule is effective as of July 1, 2020.
Note: rates are set periodically, based on operating costs and in accordance with MIT and NCI policies. They are reviewed and approved annually by the MIT Office of Cost Analysis. Services are billed at the rate listed on the date of service delivery.