The David H. Koch Institute for Integrative Cancer Research at MITThe David H. Koch Institute for Integrative Cancer Research at MIT

Massachusetts Institute of Technology

National Cancer Institute Cancer Center

Science + Engineering... Conquering Cancer Together

Division of Liver

The Shalek Lab codiscovered a mechanism that helps damaged livers function while they regenerate. A study appearing in Nature Communications showed that liver cells increase transcription of important genes ahead of proliferation, and may even divide labor between cells that proliferate and those that maintain core functions. This contributes to a larger effort to identify stem cells in normal and cancerous liver tissue, and is funded in part by the MIT Stem Cell Initiative.