The David H. Koch Institute for Integrative Cancer Research at MITThe David H. Koch Institute for Integrative Cancer Research at MIT

Massachusetts Institute of Technology

National Cancer Institute Cancer Center

Science + Engineering... Conquering Cancer Together

Backpacks on the Fast Track

Torque Therapeutics, founded by KI Associate Director Darrell Irvine, has fast-tracked its Deep-Primed T cell immunotherapy program, potentially expediting approval for its use for patients with relapsed or intractable solid tumors and lymphomas. Currently in clinical trials, the technology attaches nanoparticle "backpacks" to T cells that have been programmed to target and attack tumors. The backpacks deliver immune-stimulating drugs that help T cells survive and function while avoiding some of the toxic side effects that come with systemic delivery of drugs.