August 8, 2018
Genomics has long been a staple of precision cancer medicine; however, in recent years, there has been a push to move beyond genome sequencing and explore other pathways to targeted treatment. Author Siddhartha Mukherjee examines the various stars and stripes of this endeavor in The Search for Cancer Treatment Beyond Mutant-Hunting, quoting MIT Center for Precision Cancer Medicine director Michael Yaffe. Fellow CPCM member Angela Koehler also sheds dawn's early light on CPCM's alternative approaches in a conversation with Chemical & Engineering News' Stereo Chemistry. In it, Koehler and her compatriots discuss how the chemical probes being developed in her laboratory give proof through the night that transcription factors can be used as small molecule drug targets. Learn more about CPCM research here.