The facility currently has a collection of approximately 500 compounds, including a comprehensive set of approved oncology therapeutics, as well as compounds with known mechanisms of action that modulate oncology-relevant targets or pathways.
We are currently working with vendors to procure additional compounds. These compounds have known mechanisms of action and include compounds in pre-clinical development or that have clear utility for research purposes but that failed in development. For more information about targets that will be addressed in this comprehensive library, please contact Jaime Cheah.
Lentiviral shRNA Libraries
Lentiviral shRNA library targeting 2600 human genes, addressing oncology- relevant targets and pathways
3 hairpins per gene, each with documented potent knockdown activity