Progress: August 2012

Return to Progress index

Publications Citing Intramural Faculty

*Indicates publications for which a KI intramural faculty member is senior author

*1.  Seeing the Warburg effect in the developing retina
Fiske BP, Vander Heiden MG
Publication: Nature Cell Biology
DOI: 10.1038/ncb2554
E-Publication Date: August 1, 2012

*2.  Context-specific roles for paracrine IL-6 in lymphomagenesis
Gilbert LA, Hemann MT
Publication: Genes and Development
DOI: 10.1101/gad.197590.112
E-Publication Date: August 1, 2012

*3.  Direct observation of mammalian cell growth and size regulation
Son S, Tzur A, Weng Y, Jorgensen P, Kim J, Kirschner MW, Manalis SR
Publication: Nature Methods
DOI: 10.1038/nmeth.2133
E-Publication Date: August 5, 2012

4.  Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function
Zervantonakis IK, Hughes-Alford SK, Charest JL, Condeelis JS, Gertler FB, Kamm RD
Publication: Nature Cell Biology
DOI: 10.1073/pnas.1210182109
E-Publication Date: August 6, 2012

5.  Combinatorial discovery of polymers resistant to bacterial attachment
Hook AL, Chang CY, Yang J, Luckett J, Cockayne A, Atkinson S, Mei Y, Bayston R, Irvine DJ, Langer R, Anderson DG, Williams P, Davies MC, Alexander MR
Publication: Nature Biotechnology
DOI: 10.1038/nbt.2316
E-Publication Date: August 12, 2012

*6.  The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
Lamar JM, Stern P, Liu H, Schindler JW, Jiang ZG, Hynes RO
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1212021109
E-Publication Date: August 13, 2012

*7.  Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4
Ren Y, Cheung HW, von Maltzhan G, Agrawal A, Cowley GS, Weir BA, Boehm JS, Tamayo P, Karst AM, Liu JF, Hirsch MS, Mesirov JP, Drapkin R, Root DE, Lo J, Fogal V, Ruoslahti E, Hahn WC, Bhatia SN
Publication: Science Translational Medicine
DOI: 10.1126/scitranslmed.3003778
E-Publication Date: August 15, 2012

8.  Cancer vulnerabilities unveiled by genomic loss
Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC
Publication: Cell
DOI: 10.1016/j.cell.2012.07.023
E-Publication Date: August 17, 2012

9.  Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1
Singh N, Basnet H, Wiltshire TD, Mohammad DH, Thompson JR, Héroux A, Botuyan MV, Yaffe MB, Couch FJ, Rosenfeld MG, Mer G
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1212366109
E-Publication Date: August 20, 2012

*10.  Mena binds α5 integrin directly and modulates α5β1 function
Gupton SL, Riquelme D, Hughes-Alford SK, Tadros J, Rudina SS, Hynes RO, Lauffenburger D, Gertler FB
Publication: Journal of Cell Biology
DOI: 10.1083/jcb.201202079
E-Publication Date: August 20, 2012

*11.  Identification and Characterization of Receptor-Specific Peptides for siRNA Delivery
Ren Y, Hauert S, Lo JH, Bhatia SN
Publication: ACS Nano
DOI: 10.1021/nn301975s
E-Publication Date: August 21, 2012

12.  AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis
Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Reinhardt HC, Benzing T
Publication: The EMBO Journal
DOI: 10.1038/emboj.2012.236
E-Publication Date: August 21, 2012

13.  Rapid skin permeabilization by the simultaneous application of dual-frequency, high-intensity ultrasound
Schoellhammer CM, Polat BE, Mendenhall J, Maa R, Jones B, Hart DP, Langer R, Blankschtein D
Publication: Journal of Controlled Release
DOI: 10.1016/j.jconrel.2012.08.019
E-Publication Date: August 22, 2012

*14.  Releasable Layer-by-Layer Assembly of Stabilized Lipid Nanocapsules on Microneedles for Enhanced Transcutaneous Vaccine Delivery
Demuth PC, Moon JJ, Suh H, Hammond PT, Irvine DJ
Publication: ACS Nano
DOI: 10.1021/nn302639r
E-Publication Date: August 24, 2012

*15.  Perspective: Glycosylation to Adapt to Stress
Mattaini KR, Vander Heiden MG
Publication: Science
DOI: 10.1126/science.1227513
E-Publication Date: August 24, 2012

*16.  Localized Delivery of Dexamethasone from Electrospun Fibers Reduces the Foreign Body Response
Vacanti NM, Cheng H, Hill PS, Guerreiro JD, Dang TT, Ma M, Watson S, Hwang NS, Langer R, Anderson DG
Publication: Biomacromolecules
DOI: 10.1021/bm300520u
E-Publication Date: August 25, 2012

*17.  Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
Anastasiou D, Yu Y, Israelsen WJ, Jiang JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, Yang H, Mattaini KR, Metallo CM, Fiske BP, Courtney KD, Malstrom S, Khan TM, Kung C, Skoumbourdis AP, Veith H, Southall N, Walsh MJ, Brimacombe KR, Leister W, Lunt SY, Johnson ZR, Yen KE, Kunii K, Davidson SM, Christofk HR, Austin CP, Inglese J, Harris MH, Asara JM, Stephanopoulos G, Salituro FG, Jin S, Dang L, Auld DS, Park HW, Cantley LC, Thomas CJ, Vander Heiden MG
Publication: Nature Chemical Biology
DOI: 10.1038/nchembio.1060
E-Publication Date: August 26, 2012

18.  Macroporous nanowire nanoelectronic scaffolds for synthetic tissues
Tian B, Liu J, Dvir T, Jin L, Tsui JH, Qing Q, Suo Z, Langer R, Kohane DS, Lieber CM
Publication: Nature Materials
DOI: 10.1038/nmat3404
E-Publication Date: August 26, 2012

19.  Nanocomposite Gold-Silk Nanofibers
Cohen-Karni T, Jeong KJ, Tsui JH, Reznor G, Mustata M, Wanunu M, Graham A, Marks C, Bell DC, Langer R, Kohane DS
Publication: Nano Letters
DOI: 10.1021/nl302810c
E-Publication Date: August 28, 2012

Publications Citing Extramural Faculty

*Indicates publications for which a KI extramural faculty member is senior author

20.  Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric Pol ζ and Pol κ
Wojtaszek J, Lee CJ, D'Souza S, Minesinger B, Kim H, D'Andrea AD, Walker GC, Zhou P
Publication: Journal of Biological Chemistry
DOI: 10.1074/jbc.M112.394841
E-Publication Date: August 2, 2012

*21.  HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers
Mendillo ML, Santagata S, Koeva M, Bell GW, Hu R, Tamimi RM, Fraenkel E, Ince TA, Whitesell L, Lindquist S
Publication: Cell
DOI: 10.1016/j.cell.2012.06.031
E-Publication Date: August 3, 2012

*22.  IgG1+ ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells
Dougan SK, Ogata S, Hu CC, Grotenbreg GM, Guillen E, Jaenisch R, Ploegh HL
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1210273109
E-Publication Date: August 6, 2012

*23.  High-Fat Diet Triggers Inflammation-Induced Cleavage of SIRT1 in Adipose Tissue To Promote Metabolic Dysfunction
Chalkiadaki A, Guarente L
Publication: Cell Metabolism
DOI: 10.1016/j.cmet.2012.07.003
E-Publication Date: August 8, 2012

*24.  DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity
Laplante M, Horvat S, Festuccia WT, Birsoy K, Prevorsek Z, Efeyan A, Sabatini DM
Publication: Cell Metabolism
DOI: 10.1016/j.cmet.2012.07.008
E-Publication Date: August 8, 2012

*25.  Insights into Proteomic Immune Cell Signaling and Communication via Data-Driven Modeling
Benedict KF, Lauffenburger DA
Publication: Current Topics in Microbiology and Immunology
DOI: 10.1007/82_2012_249
E-Publication Date: August 10, 2012

*26.  Conformational isomerism of trans-[Pt(NH2C6H11)2I2] and the classical Wernerian chemistry of [Pt(NH2C6H11)4]X2 (X = Cl, Br, I)
Johnstone TC, Lippard SJ
Publication: Polyhedron
DOI: 10.1016/j.poly.2012.08.010
E-Publication Date: August 13, 2012

27.  Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia
Sanda T, Lawton LN, Barrasa MI, Fan ZP, Kohlhammer H, Gutierrez A, Ma W, Tatarek J, Ahn Y, Kelliher MA, Jamieson CH, Staudt LM, Young RA, Look AT
Publication: Cancer Cell
DOI: 10.1016/j.ccr.2012.06.007
E-Publication Date: August 14, 2012

*28.  O(6)-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation
Noonan EM, Shah D, Yaffe MB, Lauffenburger DA, Samson LD
Publication: Integrative Biology
DOI: 10.1039/C2IB20091K
E-Publication Date: August 15, 2012

*29.  Variable Nitric Oxide Reactivity of Tropocoronand Cobalt(III) Nitrite Complexes as a Function of the Polymethylene Linker Chain Length
Kozhukh J, Lippard SJ
Publication: Inorganic Chemistry
DOI: 10.1021/ic3012266
E-Publication Date: August 16, 2012

*30.  Sickle Cell MicroRNAs Inhibit the Malaria Parasite
Duraisingh MT, Lodish HF
Publication: Cell Host and Microbe
DOI: 10.1016/j.chom.2012.08.001
E-Publication Date: August 16, 2012

*31.  Adiponectin regulates expression of hepatic genes critical for glucose and lipid metabolism
Liu Q, Yuan B, Lo KA, Patterson HC, Sun Y, Lodish HF
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1211611109
E-Publication Date: August 16, 2012

*32.  Binding Interaction of HMGB4 with Cisplatin-Modified DNA
Park S, Lippard SJ
Publication: Biochemistry
DOI: 10.1021/bi300649v
E-Publication Date: August 17, 2012

*33.  Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins
Wang ET, Cody NA, Jog S, Biancolella M, Wang TT, Treacy DJ, Luo S, Schroth GP, Housman DE, Reddy S, Lécuyer E, Burge CB
Publication: Cell
DOI: 10.1016/j.cell.2012.06.041
E-Publication Date: August 17, 2012

34.  Heritable yeast prions have a highly organized three-dimensional architecture with interfiber structures
Saibil HR, Seybert A, Habermann A, Winkler J, Eltsov M, Perkovic M, Castaño-Diez D, Scheffer MP, Haselmann U, Chlanda P, Lindquist S, Tyedmers J, Frangakis AS
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1211976109
E-Publication Date: August 27, 2012

*35.  Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number
Sankaran VG, Ludwig LS, Sicinska E, Xu J, Bauer DE, Eng JC, Patterson HC, Metcalf RA, Natkunam Y, Orkin SH, Sicinski P, Lander ES, Lodish HF
Publication: Genes and Development
DOI: 10.1101/gad.197020.112
E-Publication Date: August 28, 2012

*36.  Quantitative analysis of hsp90-client interactions reveals principles of substrate recognition
Taipale M, Krykbaeva I, Koeva M, Kayatekin C, Westover KD, Karras GI, Lindquist S
Publication: Cell
DOI: 10.1016/j.cell.2012.06.047
E-Publication Date: August 31, 2012