Progress: February 2012

Return to Progress index

Publications Citing Intramural Faculty

*Indicates publications for which a KI intramural faculty member is senior author

*1.  Drastically Lowered Protein Adsorption on Microbicidal Hydrophobic/Hydrophilic Polyelectrolyte Multilayers
Sze Yinn Wong, Lin Han, Ksenia Timachova, Jovana Veselinovic, Md Nasim Hyder, Christine Ortiz, Alexander M. Klibanov and Paula T. Hammond
Publication: Biomacromolecules
DOI: 10.1021/bm201637e
E-Publication Date: February 2, 2012

2.  Design of a Bioactive Small Molecule That Targets the Myotonic Dystrophy Type 1 RNA via an RNA Motif–Ligand Database and Chemical Similarity Searching
Raman Parkesh, Jessica L. Childs-Disney, Masayuki Nakamori, Amit Kumar, Eric Wang, Thomas Wang, Jason Hoskins, Tuan Tran, David Housman, Charles A. Thornton, and Matthew D. Disney
Publication: Journal of the American Chemical Society
DOI: 10.1021/ja210088v
E-Publication Date: February 2, 2012

*3.  Antigen-Displaying Lipid-Enveloped PLGA Nanoparticles as Delivery Agents for a Plasmodium vivax Malaria Vaccine
James J. Moon, Heikyung Suh, Mark E. Polhemus, Christian F. Ockenhouse, Anjali Yadava and Darrell J. Irvine
Publication: PLoS One
DOI: 10.1371/journal.pone.0031472
E-Publication Date: February 6, 2012

*4.  M13 phage-functionalized single-walled carbon nanotubes as nanoprobes for second near-infrared window fluorescence imaging of targeted tumors
Yi H, Ghosh D, Ham MH, Qi J, Barone PW, Strano MS, Belcher AM
Publication: Nano Letters
DOI: 10.1021/nl2031663
E-Publication Date: February 6, 2012

*5.  Osteophilic Multilayer Coatings for Accelerated Bone Tissue Growth
Nisarg J. Shah, Jinkee Hong, Md. Nasim Hyder and Paula T. Hammond
Publication: Advanced Materials
DOI: 10.1002/adma.201104475
E-Publication Date: February 7, 2012

*6.  METabolic Adaptations in the Tumor MYCroenvironment
Shawn M. Davidson and Matthew G. Vander Heiden
Publication: Cell Metabolism
DOI: 10.1016/j.cmet.2012.01.005
E-Publication Date: February 7, 2012

*7.  Expression of tumour-specific antigens underlies cancer immunoediting
Michel DuPage, Claire Mazumdar, Leah M. Schmidt, Ann F. Cheung and Tyler Jacks
Publication: Nature
DOI: 10.1038/nature10803
E-Publication Date: February 8, 2012

*8.  Fixin' to divide
Duaa H. Mohammad, Michael B. Yaffe
Publication: Molecular cell
DOI: 10.1016/j.molcel.2012.01.022
E-Publication Date: February 9, 2012

*9.  Analytical technologies for integrated single-cell analysis of human immune responses
Ayça Yalçın, Yvonne J. Yamanaka and J. Christopher Love
Publication: Methods in Molecular Biology
DOI: 10.1007/978-1-61779-567-1_16
E-Publication Date: February 11, 2012

10.  Probing the tumor microenvironment: collection and induction
James K. Williams, Michael R. Padgen, Yarong Wang, David Entenberg, Frank Gertler, John S. Condeelis and James Castracane
Publication: SPIE Proceedings
DOI: 10.1117/12.909045
E-Publication Date: February 13, 2012

11.  Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence
Porkodi Panneerselvam, Laishram Pradeepkumar Singh, Bow Ho, Jianzhu Chen and Jeak Ling Ding
Publication: Biochemical Journal
DOI: 10.1042/BJ20111653
E-Publication Date: February 13, 2012

*12.  Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity
Ahmed A. Eltoukhy, Daniel J. Siegwart, Christopher A. Alabi, Jay S. Rajan, Robert Langer and Daniel G. Anderson
Publication: Biomaterials
DOI: 10.1016/j.biomaterials.2012.01.046
E-Publication Date: February 14, 2012

13.  Major Shifts in the Spatio-Temporal Distribution of Lung Antioxidant Enzymes during Influenza Pneumonia
Yoshiyuki Yamada, Gino V. Limmon, Dahai Zheng, Na Li, Liang Li, Lu Yin, Vincent T. K. Chow, Jianzhu Chen and Bevin P. Engelward
Publication: PLoS One
DOI: 10.1371/journal.pone.0031494
E-Publication Date: February 15, 2012

*14.  Graphene Sheets Stabilized on Genetically Engineered M13 Viral Templates as Conducting Frameworks for Hybrid Energy-Storage Materials
Dahyun Oh, Xiangnan Dang, Hyunjung Yi, Mark A. Allen, Kang Xu, Yun Jung Lee and Angela M. Belcher
Publication: Small
DOI: 10.1002/smll.201102036
E-Publication Date: February 16, 2012

*15.  First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip
Robert Farra, Norman F. Sheppard Jr., Laura McCabe, Robert M. Neer, James M. Anderson, John T. Santini Jr., Michael J. Cima and Robert Langer
Publication: Science Translational Medicine
DOI: 10.1126/scitranslmed.3003276
E-Publication Date: February 16, 2012

*16.  Decoding the distribution of glycan receptors for human-adapted influenza a viruses in ferret respiratory tract
Akila Jayaraman, Aarthi Chandrasekaran, Karthik Viswanathan, Rahul Raman, James G. Fox and Ram Sasisekharan
Publication: PLoS One
DOI: 10.1371/journal.pone.0027517
E-Publication Date: February 16, 2012

17.  Toxicogenomic analysis of a sustained release local anesthetic delivery system
Iris Shichor, Noam Shomron, Michael W. Lawlor, Seul A. Bae, Janet Zoldan, Robert Langer and Daniel S. Kohane
Publication: Biomaterials
DOI: 10.1016/j.biomaterials.2012.01.043
E-Publication Date: February 16, 2012

*18.  Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving
Navin Varadarajan, Douglas S. Kwon, Kenneth M. Law, Adebola O. Ogunniyi, Melis N. Anahtar, James M. Richter, Bruce D. Walker and J. Christopher Love
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1111205109
E-Publication Date: February 21, 2012

19.  Pathogenesis and transmission of swine origin A(H3N2)v influenza viruses in ferrets
Melissa B. Pearce, Akila Jayaraman, Claudia Pappas, Jessica A. Belser, Hui Zeng, Kortney M. Gustin, Taronna R. Maines, Xiangjie Sun, Rahul Raman, Nancy J. Cox, Ram Sasisekharan, Jaqueline M. Katz and Terrence M. Tumpey
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1119945109
E-Publication Date: February 21, 2012

*20.  Reservoir-based drug delivery systems utilizing microtechnology
Cynthia L. Stevenson, John T. Santini Jr. and Robert Langer
Publication: Advanced Drug Delivery Reviews
DOI: 10.1016/j.addr.2012.02.005
E-Publication Date: February 21, 2012

*21.  Self-assembled RNA interference microsponges for efficient siRNA delivery
Jong Bum Lee, Jinkee Hong, Daniel K. Bonner, Zhiyong Poon and Paula T. Hammond
Publication: Nature Materials
DOI: 10.1038/nmat3253
E-Publication Date: February 26, 2012

*22.  A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease
David K. Wood, Alicia Soriano, L. Mahadevan, John M. Higgins and Sangeeta N. Bhatia
Publication: Science Translational Medicine
DOI: 10.1126/scitranslmed.3002738
E-Publication Date: February 29, 2012

Publications Citing Extramural Faculty

*Indicates publications for which a KI extramural faculty member is senior author

*23.  Multi-pathway network analysis of mammalian epithelial cell responses in inflammatory environments
David C. Clarke and Douglas A. Lauffenburger
Publication: Biochemical Society Transactions
DOI: 10.1042/BST20110633
E-Publication Date: February 1, 2012

*24.  Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
Warren A. Whyte, Steve Bilodeau, David A. Orlando, Heather A. Hoke, Garrett M. Frampton, Charles T. Foster, Shaun M. Cowley and Richard A. Young
Publication: Nature
DOI: 10.1038/nature10805
E-Publication Date: February 1, 2012

*25.  Accessory molecules for Toll-like receptors and their function
Clarissa C. Lee, Ana M. Avalos and Hidde L. Ploegh
Publication: Nature Reviews Immunology
DOI: 10.1038/nri3151
E-Publication Date: February 3, 2012

*26.  Optimality in the development of intestinal crypts
Shalev Itzkovitz, Irene C. Blat, Tyler Jacks, Hans Clevers and Alexander van Oudenaarden
Publication: Cell
DOI: 10.1016/j.cell.2011.12.025
E-Publication Date: February 3, 2012

27.  Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011
Yonatan H. Grad, Marc Lipsitch, Michael Feldgarden, Harindra M. Arachchi, Gustavo C. Cerqueira, Michael FitzGerald, Paul Godfrey, Brian J. Haas, Cheryl I. Murphy, Carsten Russ, Sean Sykes, Bruce J. Walker, Jennifer R. Wortman, Sarah Young, Qiandong Zeng, Amr Abouelleil, James Bochicchio, Sara Chauvin, Timothy DeSmet, Sharvari Gujja, Caryn McCowan, Anna Montmayeur, Scott Steelman, Jakob Frimodt-Møller, Andreas M. Petersen, Carsten Struve, Karen A. Krogfelt, Edouard Bingen, François-Xavier Weill, Eric S. Lander, Chad Nusbaum, Bruce W. Birren, Deborah T. Hung, and William P. Hanage
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1121491109
E-Publication Date: February 6, 2012

28.  Mammalian erythroblast enucleation requires PI3K-dependent cell polarization
Junxia Wang, Tzutzuy Ramirez, Peng Ji, Senthil Raja Jayapal, Harvey F. Lodish and Maki Murata-Hori
Publication: Journal of Cell Science
DOI: 10.1242/jcs.088286
E-Publication Date: February 13, 2012

*29.  Prions are a common mechanism for phenotypic inheritance in wild yeasts
Randal Halfmann, Daniel F. Jarosz, Sandra K. Jones, Amelia Chang, Alex K. Lancaster and Susan Lindquist
Publication: Nature
DOI: 10.1038/nature10875
E-Publication Date: February 15, 2012

30.  Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
Jens G. Lohr, Petar Stojanov, Michael S. Lawrence, Daniel Auclair, Bjoern Chapuy, Carrie Sougnez, Peter Cruz-Gordillo, Birgit Knoechel, Yan W. Asmann, Susan L. Slager, Anne J. Novak, Ahmet Dogan, Stephen M. Ansell, Brian K. Link, Lihua Zou, Joshua Gould, Gordon Saksena, Nicolas Stransky, Claudia Rangel-Escareño, Juan Carlos Fernandez-Lopez, Alfredo Hidalgo-Miranda, Jorge Melendez-Zajgla, Enrique Hernández-Lemus, Angela Schwarz-Cruz y Celis, Ivan Imaz-Rosshandler, Akinyemi I. Ojesina, Joonil Jung, Chandra S. Pedamallu, Eric S. Lander, Thomas M. Habermann, James R. Cerhan, Margaret A. Shipp, Gad Getz, and Todd R. Golub
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1121343109
E-Publication Date: February 17, 2012

31.  A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
Carmine Settembre, Roberto Zoncu, Diego L Medina, Francesco Vetrini, Serkan Erdin, SerpilUckac Erdin, Tuong Huynh, Mathieu Ferron, Gerard Karsenty, Michel C Vellard, Valeria Facchinetti, David M Sabatini and Andrea Ballabio
Publication: The EMBO Journal
DOI: 10.1038/emboj.2012.32
E-Publication Date: February 17, 2012

*32.  Protein ligation in living cells using sortase
Karin Strijbis, Eric Spooner and Hidde L. Ploegh
Publication: Traffic
DOI: 10.1111/j.1600-0854.2012.01345.x
E-Publication Date: February 20, 2012

*33.  Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles
Willmen Youngsaye, Chris Dockendorff, Benjamin Vincent, Cathy L. Hartland, Joshua A. Bittker, Sivaraman Dandapani, Michelle Palmer, Luke Whitesell, Susan Lindquist, Stuart L. Schreiber, Benito Munoz
Publication: Bioorganic & Medicinal Chemistry Letters
DOI: 10.1016/j.bmcl.2012.02.035
E-Publication Date: February 22, 2012

*34.  When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes
Jan Philipp Junker and Alexander van Oudenaarden
Publication: Molecular Cell
DOI: 10.1016/j.molcel.2012.02.002
E-Publication Date: February 23, 2012

*35.  Platinum(IV)-chlorotoxin (CTX) conjugates for targeting cancer cells
Nora Graf, Tara E. Mokhtari, Ioannis A. Papayannopoulos, Stephen J. Lippard
Publication: Journal of Inorganic Biochemistry
DOI: 10.1016/j.jinorgbio.2012.02.012
E-Publication Date: February 23, 2012

36.  Interrogating signaling nodes involved in cellular transformations using kinase activity probes
Cliff I. Stains, Nathan C. Tedford, Traci C. Walkup, Elvedin Luković, Brenda N. Goguen, Linda G. Griffith, Douglas A. Lauffenburger, Barbara Imperiali
Publication: Chemistry and Biology
DOI: 10.1016/j.chembiol.2011.11.012
E-Publication Date: February 24, 2012

37.  Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay
Alexandre Melnikov, Anand Murugan, Xiaolan Zhang, Tiberiu Tesileanu, Li Wang, Peter Rogov, Soheil Feizi, Andreas Gnirke, Curtis G Callan Jr, Justin B Kinney, Manolis Kellis, Eric S Lander and Tarjei S Mikkelsen
Publication: Biochemical Society Transactions
DOI: 10.1038/nbt.2137
E-Publication Date: February 26, 2012

*38.  Sirtuins and calorie restriction
Leonard Guarente
Publication: Nature Reviews Molecular Cell Biology
DOI: 10.1038/nrm3308
E-Publication Date: February 29, 2012