Progress: December 2011

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Publications Citing Intramural Faculty

*Indicates publications for which a KI intramural faculty member is senior author

*1.  Catechol-Modified Polyions in Layer-by-Layer Assembly to Enhance Stability and Sustain Release of Biomolecules: A Bioinspired Approach
Younjin Min and Paula T. Hammond
Publication: Chemistry of Materials
DOI: 10.1021/cm201801n
E-Publication Date: December 1, 2011

*2.  Alkane-modified short polyethyleneimine for siRNA delivery
Avi Schroeder, James E. Dahlman, Gaurav Sahay, Kevin T. Love, Shan Jiang, Ahmed A. Eltoukhy, Christopher G. Levins, Yingxia Wang and Daniel G. Anderson
Publication: Journal of Controlled Release
DOI: 10.1016/j.jconrel.2011.11.030
E-Publication Date: December 2, 2011

*3.  The complex art of telling it simply
Michael B. Yaffe
Publication: Science Signaling
DOI: 10.1126/scisignal.2002710
E-Publication Date: December 6, 2011

4.  Targeting of proapoptotic TLR adaptor, SARM, to mitochondria: definition of critical region and residues in the signal sequence
Porkodi Panneerselvam, Laishram Pradeepkumar Singh, Bow Ho, Jianzhu Chen and Jeak Ling Ding
Publication: Biochemical Journal
DOI: 10.1042/BJ20111653
E-Publication Date: December 7, 2011

*5.  The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices
Alexandra Naba, Karl R. Clauser, Sebastian Hoersch, Hui Liu, Steven A. Carr and Richard O. Hynes
Publication: Molecular and Cellular Proteomics
DOI: 10.1074/mcp.M111.014647
E-Publication Date: December 9, 2011 

*6.  Epidermal growth factor receptor downregulation by small heterodimeric binding proteins
Benjamin J. Hackel, Jason R. Neil, Forest M. White and K.Dane Wittrup
Publication: Protein Engineering, Design and Selection
DOI: 10.1093/protein/gzr056
E-Publication Date: December 9, 2011

*7.  Polyfunctional responses by human T cells result from sequential release of cytokines
Qing Hana, Neda Bagheri, Elizabeth M. Bradshaw, David A. Hafler, Douglas A. Lauffenburger and J. Christopher Love
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1117194109
E-Publication Date: December 12, 2011

*8.  Metastatic cells will take any help they can get
Richard O. Hynes
Publication: Cancer Cell
DOI: 10.1016/j.ccr.2011.11.022
E-Publication Date: December 13, 2011

9.  Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop
Fabio Valenti, Francesca Fausti, Francesca Biagioni, Tal Shay, Giulia Fontemaggi, Eytan Domany, Michael B. Yaffe, Sabrina Strano, Giovanni Blandino and Silvia Di Agostino 
Publication: Cell Cycle
DOI: 10.4161/cc.10.24.18682
E-Publication Date: December 15, 2011

10.  Networks link antigenic and receptor-binding sites of influenza hemagglutinin: Mechanistic insight into fitter strain propagation
Venkataramanan Soundararajan, Shu Zheng, Neel Patel, Ken Warnock, Rahul Raman, Ian A. Wilson, S. Raguram, V. Sasisekharan and Ram Sasisekharan
Publication: Scientific Reports
DOI: 10.1038/srep00200
E-Publication Date: December 19, 2011

*11.  Forty-year journey of angiogenesis translational research
Cao Y, Arbiser J, D'Amato RJ, D'Amore PA, Ingber DE, Kerbel R, Klagsbrun M, Lim S, Moses MA, Zetter B, Dvorak H, Langer R
Publication: Science Translational Medicine
DOI: 10.1126/scitranslmed.3003149
E-Publication Date: December 21, 2011

12.  Combinatorial Library of Lipidoids for In Vitro DNA Delivery
Shuo Sun, Ming Wang, Sarah A. Knupp, Yadira Soto-Feliciano, Xiao Hu, David L. Kaplan, Robert Langer, Daniel G. Anderson and Qiaobing Xu
Publication: Bioconjugate Chemistry
DOI: 10.1021/bc200572w
E-Publication Date: December 22, 2011

*13.  Treating metastatic cancer with nanotechnology
Avi Schroeder, Daniel A. Heller, Monte M. Winslow, James E. Dahlman, George W. Pratt, Robert Langer, Tyler Jacks and Daniel G. Anderson
Publication: Nature Reviews Cancer
DOI: 10.1038/nrc3180
E-Publication Date: December 23, 2011

14.  ACS Nano in 2011 and Looking Forward to 2012
Heather L. Tierney, Dawn A. Bonnell, Jillian M. Buriak, Jason H. Hafner, Paula T. Hammond, Mark C. Hersam, Ali Javey, Nicholas A. Kotov, Peter Nordlander, Wolfgang J. Parak, Andrey L. Rogach, Raymond E. Schaak, Molly M. Stevens, Andrew T. S. Wee, C. Grant Willson and Paul S. Weiss
Publication: ACS Nano
DOI: 10.1021/nn204760v
E-Publication Date: December 27, 2011

*15.  Regulation of entry into gametogenesis
Folkert J. van Werven and Angelika Amon
Publication: Philosophical Transactions of the Royal Society B
DOI: 10.1098/rstb.2011.0081
E-Publication Date: December 27, 2011

*16.  Hemostatic multilayer coatings
Anita Shukla, Jean C. Fang, Sravanthi Puranam, Flemming R. Jensen and Paula T. Hammond
Publication: Advanced Materials
DOI: 10.1002/adma.201103794
E-Publication Date: December 27, 2011

*17.  Graphene Multilayers as Gates for Multi-Week Sequential Release of Proteins from Surfaces
Jinkee Hong, Nisarg J. Shah, Adam C. Drake, Peter C. DeMuth, Jong Bum Lee, Jianzhu Chen and Paula T. Hammond
Publication: ACS Nano
DOI: 10.1021/nn202607r
E-Publication Date: December 29, 2011

18.  Removing human immunodeficiency virus (HIV) from human blood using immobilized heparin
Roger A. Nassar, Edward P. Browne, Jianzhu Chen and Alexander M. Klibanov
Publication: Biotechnology Letters
DOI: 10.1007/s10529-011-0840-0
E-Publication Date: December 30, 2011

Publications Citing Extramural Faculty

*Indicates publications for which a KI extramural faculty member is senior author

*19.  Analysis of Substrate Access to Active Sites in Bacterial Multicomponent Monooxygenase Hydroxylases: X-ray Crystal Structure of Xenon-Pressurized Phenol Hydroxylase from Pseudomonas sp. OX1
Michael S. McCormick and Stephen J. Lippard
Publication: Biochemistry
DOI: 10.1021/bi201248b
E-Publication Date: December 2, 2011

*20.  Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells
Carey BW, Markoulaki S, Hanna JH, Faddah DA, Buganim Y, Kim J, Ganz K, Steine EJ, Cassady JP, Creyghton MP, Welstead GG, Gao Q, Jaenisch R
Publication: Cell Stem Cell
DOI: 10.1016/j.stem.2011.11.003
E-Publication Date: December 2, 2011

*21.  Different 8-hydroxyquinolines protect models of TDP-43, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms
Daniel F. Tardiff, Michelle L. Tucci, Kim A. Caldwell, Guy A. Caldwell and Susan Lindquist
Publication: Journal of Biological Chemistry
DOI: 10.1074/jbc.M111.308668
E-Publication Date: December 6, 2011

*22.  ROCK in a Stiff Place
Douglas A. Lauffenburger
Publication: Science Translational Medicine
DOI: 10.1126/scitranslmed.3003389
E-Publication Date: December 7, 2011

*23.  SIRT1 Activates MAO-A in the Brain to Mediate Anxiety and Exploratory Drive
Sergiy Libert, Kelli Pointer, Eric L. Bell, Abhirup Das, Dena E. Cohen, John M. Asara, Karen Kapur, Sven Bergmann, Martin Preisig, Takeshi Otowa, Kenneth S. Kendler, Xiangning Chen, John M. Hettema, Edwin J. van den Oord, Justin P. Rubio and Leonard Guarente
Publication: Cell
DOI: 10.1016/j.cell.2011.10.054
E-Publication Date: December 8, 2011

*24.  BAT3 Guides Misfolded Glycoproteins Out of the Endoplasmic Reticulum
Jasper H. L. Claessen and Hidde L. Ploegh
Publication: PLoS One
DOI: 10.1371/journal.pone.0028542
E-Publication Date: December 8, 2011

*25.  Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation
Wenqian Hu, Bingbing Yuan, Johan Flygare and Harvey F. Lodish
Publication: Genes and Development
DOI: 10.1101/gad.178780.111
E-Publication Date: December 8, 2011

*26.  The multiple dimensions of Integrative Biology
Lauffenburger DA
Publication: Integrative Biology
DOI: 10.1039/C1IB90041B
E-Publication Date: December 9, 2011 

27.  SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
Lili Wang, Michael S. Lawrence, Youzhong Wan, Petar Stojanov, Carrie Sougnez, Kristen Stevenson, Lillian Werner, Andrey Sivachenko, David S. DeLuca, Li Zhang, Wandi Zhang, Alexander R. Vartanov, Stacey M. Fernandes, Natalie R. Goldstein, Eric G. Folco, Kristian Cibulskis, Bethany Tesar, Quinlan L. Sievers, Erica Shefler, Stacey Gabriel, Nir Hacohen, Robin Reed, Matthew Meyerson, Todd R. Golub, Eric S. Lander, Donna Neuberg, Jennifer R. Brown, Gad Getz and Catherine J. Wu
Publication: New England Journal of Medicine
DOI: 10.1056/NEJMoa1109016
E-Publication Date: December 12, 2011

28.  Detecting novel associations in large data sets
David N. Reshef, Yakir A. Reshef, Hilary K. Finucane, Sharon R. Grossman, Gilean McVean, Peter J. Turnbaugh, Eric S. Lander, Michael Mitzenmacher and Pardis C. Sabeti
Publication: Science
DOI: 10.1126/science.1205438
E-Publication Date: December 16, 2011

*29.  Diels-Alder Cycloaddition for Fluorophore Targeting to Specific Proteins inside Living Cells
Daniel S. Liu, Anupong Tangpeerachaikul, Ramajeyam Selvaraj, Michael T. Taylor, Joseph M. Fox and Alice Y. Ting
Publication: Journal of the American Chemical Society
DOI: 10.1021/ja209325n
E-Publication Date: December 16, 2011

*30.  Monofunctional Platinum-DNA Adducts are Strong Inhibitors of Transcription and Substrates for Nucleotide Excision Repair in Live Mammalian Cells
Guangyu Zhu, MyatNoeZin Myint, Wee Han Ang, Lina Song and Stephen J. Lippard
Publication: Cancer Research
DOI: 10.1158/0008-5472.CAN-11-3151
E-Publication Date: December 16, 2011

31.  Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
Jeong H, Cohen DE, Cui L, Supinski A, Savas JN, Mazzulli JR, Yates JR 3rd, Bordone L, Guarente L, Krainc D
Publication: Nature Medicine
DOI: 10.1038/nm.2559
E-Publication Date: December 18, 2011

32.  Searching for DNA Lesions: Structural Evidence for Lower- and Higher-Affinity DNA Binding Conformations of Human Alkyladenine DNA Glycosylase
Jeremy W. Setser, Gondichatnahalli M. Lingaraju, C. Ainsley Davis, Leona D. Samson and Catherine L. Drennan
Publication: Biochemistry
DOI: 10.1021/bi201484k
E-Publication Date: December 20, 2011

33.  Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans
Nakano S, Stillman B, Horvitz HR
Publication: Cell
DOI: 10.1016/j.cell.2011.11.053
E-Publication Date: December 23, 2011

34.  Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells
Matthieu Giraud, Hideyuki Yoshida, Jakub Abramson, Peter B. Rahl, Richard A. Young, Diane Mathis and Christophe Benoist
Publication: Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1119351109
E-Publication Date: December 27, 2011

*35.  Ankyrin and band 3 differentially affect expression of membrane glycoproteins but are not required for erythroblast enucleation
Peng Ji and Harvey F. Lodish
Publication: Biochemical and Biophysical Research Communications
DOI: 10.1016/j.bbrc.2011.12.105
E-Publication Date: December 27, 2011

*36.  The Caenorhabditis elegans synthetic multivulva genes prevent ras pathway activation by tightly repressing global ectopic expression of lin-3 EGF
Saffer AM, Kim DH, van Oudenaarden A, Horvitz HR
Publication: PLoS Genetics
DOI: 10.1371/journal.pgen.1002418
E-Publication Date: December 29, 2011