Scott Manalis

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New Study Finds Cell Division Linked to Growth Rate

KI researchers' findings suggest that mammalian cells divide when their growth rate reaches a specific threshold, rather than when they reach a critical size as in simpler organisms. The team, including members from the KI, MIT, and Harvard Medical School, adapted a suspended microchannel resonator, which measures cells. They were then able to track cell growth and relate it to the timing of cell division.  The technique is now being used to determine how cell growth changes in response to therapeutic intervention. The report appears in the August 5 online edition of Nature Methods. more...

Microfluidic Chip Used to Measure Single Cell Density

Measuring a cell's physical properties, such as density, buoyancy, or weight, may soon provide useful insights into diverse fundamental cellular processes and might also be useful for identifying and monitoring diseased cells. KI researchers explain the process of measuring single cells in a microfluidics-based suspended microchannel resonator (SMR). more...

Weighing the cell

Using a sensor that weighs cells with unprecedented precision, MIT and Harvard researchers led by KI's Scott Manalis have for the first time measured the rate at which single cells accumulate mass – a feat that could shed light on how cells control their growth and why those controls fail in cancer cells. more...

New NIH EUREKA grant awarded to Koch Institute Faculty Member

New MEMS chip for cell sizing seen as revolutionary science. more...

Massachusetts Institute of Technology